SGSM1 and CETN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SGSM1	CETN2
Description		small G protein signaling modulator 1	centrin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Membrane	Intracellular Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Transcription Export Complex 2 XPC Complex
	Molecular Function	GTPase Activator Activity Rab GTPase Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Centriole Replication Spermatogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division Global Genome Nucleotide-excision Repair Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Night sleep phenotypes ( 27126917) Primary sclerosing cholangitis ( 27992413) Refractive astigmatism ( 30306274) Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		3 interacting genes: CETN1 CETN2 CETN3	8 interacting genes: ARSA ATP6AP1 CCP110 PNMA5 PRMT6 SFI1 SGSM1 XPC
Entrez ID		129049	1069
HPRD ID		18969	02051
Ensembl ID		ENSG00000167037	ENSG00000147400
Uniprot IDs		A0A087X241 Q2NKQ1	P41208
PDB IDs			1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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