PUSL1 and MIB2

		PUSL1	MIB2
Description		pseudouridine synthase like 1	mindbomb E3 ubiquitin protein ligase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Cytoplasm Early Endosome Cytosol
	Molecular Function	RNA Binding Pseudouridine Synthase Activity	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	TRNA Pseudouridine Synthesis	Protein Polyubiquitination Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Body mass index ( 26426971) Height ( 31562340) Iris color (a* coordinate) ( 30895295) Iris color (b* coordinate) ( 30895295)
Interacting Genes		6 interacting genes: APP CALML6 FBXO7 MIB2 PLEKHN1 UBE2J2	12 interacting genes: ACTA1 ACTC1 BCL10 CYLD GRIN2B JAG2 PUSL1 SRPK2 TBK1 UBE2D2 UBE2N UBE2U
Entrez ID		126789	142678
HPRD ID		08301	15905
Ensembl ID		ENSG00000169972	ENSG00000197530
Uniprot IDs		Q8N0Z8	Q96AX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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