CCR6 and AASS

		CCR6	AASS
Description		C-C motif chemokine receptor 6	aminoadipate-semialdehyde synthase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Sperm Flagellum Sperm Midpiece Sperm Principal Piece Sperm Plasma Membrane	Cytoplasm Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding Signaling Receptor Activity	Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Dendritic Cell Chemotaxis Leukocyte Migration Involved In Inflammatory Response Chemotaxis Immune Response Humoral Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Epithelial Cell Migration Calcium-mediated Signaling Isotype Switching To IgA Isotypes Cell Chemotaxis Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation Chemokine-mediated Signaling Pathway Lymphocyte Migration T Cell Migration Thymocyte Migration DN2 Thymocyte Differentiation DN3 Thymocyte Differentiation Regulation Of T Cell Migration Positive Regulation Of Dendritic Cell Chemotaxis	Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxidation-reduction Process
Pathways		Beta defensins Chemokine receptors bind chemokines G alpha (i) signalling events	Lysine catabolism
Drugs			Glutamic Acid NADH Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate N-(5-Amino-5-Carboxypentyl)Glutamic Acid
Diseases			Hyperlysinemia
GWAS		Albumin-globulin ratio ( 29403010) Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) Basal cell carcinoma ( 31174203) Crohn's disease ( 18587394 28067908 20570966 21102463 23850713) Graves' disease ( 22922229) Inflammatory bowel disease ( 27569725 28067908 23128233) Keratinocyte cancer (MTAG) ( 31174203) Lung cancer ( 28604730) Primary biliary cholangitis ( 28425483) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Rheumatoid arthritis ( 30423114 24782177 23143596 24390342 20453841 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Social autistic-like traits ( 24133439) Triglycerides ( 24886709) Vitiligo ( 20526339 27723757)
Interacting Genes		6 interacting genes: AASS CCL20 DEFB1 DEFB103B DEFB4A MARK1	6 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 PTPRZ1 WASL
Entrez ID		1235	10157
HPRD ID		03498	05489
Ensembl ID		ENSG00000112486	ENSG00000008311
Uniprot IDs		P51684	A4D0W4 Q9UDR5
PDB IDs			5L76 5L78 5O1N 5O1O 5O1P
Enriched GO Terms of Interacting Partners?
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