TTC8 and PCM1

Number of citations of the paper that reports this interaction (PubMedID 14520415)
218

Data Source:
HPRD (in vivo)

		TTC8	PCM1
Description		tetratricopeptide repeat domain 8	pericentriolar material 1
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Cilium BBSome Ciliary Basal Body Ciliary Membrane Non-motile Cilium	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Transport Establishment Of Anatomical Structure Orientation Sensory Processing Cilium Assembly Non-motile Cilium Assembly	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways		BBSome-mediated cargo-targeting to cilium	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Copper levels ( 26025379) Limited cutaneous systemic scleroderma ( 29293537) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Obesity-related traits ( 23251661) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		1 interacting genes: PCM1	39 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 NDC80 NECAB2 PCNT PRC1 PRKCI RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		123016	5108
HPRD ID		10484	02624
Ensembl ID		ENSG00000165533	ENSG00000078674
Uniprot IDs		A0A0C4DFT4 A0A0C4DGH8 A0A0C4DGX9 A0A0C4DGY3 B3KSL8 Q86U25 Q8TAM2	A2RUU9 B9EIS5 Q15154
PDB IDs			6HYL 6HYM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?