JDP2 and NEK9

		JDP2	NEK9
Description		Jun dimerization protein 2	NIMA related kinase 9
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Centrosome Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Transcription Corepressor Activity Protein Binding Protein-containing Complex Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division
Pathways			Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs		Pseudoephedrine
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Basal cell carcinoma ( 31174203) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 24076602) Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)	Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		19 interacting genes: ATF2 CREBBP EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 NEK9 PGR SNW1	18 interacting genes: BICD2 CSN2 GZMB IFT43 JDP2 LIN52 MALL MBP MPP5 NEK6 NEK7 NEK8 RAN RARG RPS6KL1 SSRP1 SUPT16H WDR33
Entrez ID		122953	91754
HPRD ID		16360	11386
Ensembl ID		ENSG00000140044	ENSG00000119638
Uniprot IDs		A0A024R6D7 Q8WYK2	Q6PKF2 Q8TD19
PDB IDs			3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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