CLNS1A and EIF4A2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CLNS1A	EIF4A2
Description		chloride nucleotide-sensitive channel 1A	eukaryotic translation initiation factor 4A2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytosol Cytoskeleton Plasma Membrane Methylosome PICln-Sm Protein Complex	Cytosol Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Spliceosomal SnRNP Assembly Chloride Transport Cell Volume Homeostasis	Cytoplasmic Translational Initiation Translational Initiation Regulation Of Translational Initiation Viral Process Negative Regulation Of RNA-directed 5'-3' RNA Polymerase Activity Cellular Response To Leukemia Inhibitory Factor
Pathways		snRNP Assembly	ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Tourette syndrome ( 30818990)
Interacting Genes		15 interacting genes: ACTB CSNK2A1 EIF4A2 EPB41 EPB41L3 ITGA2B LSM10 LSM2 LSM3 PRMT5 SNRPB SNRPD1 SNRPD2 SNRPD3 WDR77	19 interacting genes: BRCA1 CLNS1A DPPA4 ECT2 EIF4G1 EIF4G2 GOLGA2 HSPB2 IPO11 MCPH1 MDFI NEK2 PFDN1 PIH1D2 SLC16A9 SSX2IP TK1 TRIM36 TRIM39
Entrez ID		1207	1974
HPRD ID		03694	03062
Ensembl ID		ENSG00000074201	ENSG00000156976
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	Q14240
PDB IDs			3BOR
Enriched GO Terms of Interacting Partners?
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