CLCN7 and OSTM1

Number of citations of the paper that reports this interaction (PubMedID 16525474)
87

Data Source:
HPRD (in vivo)

		CLCN7	OSTM1
Description		chloride voltage-gated channel 7	osteoclastogenesis associated transmembrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Lysosomal Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Response To PH Ion Transmembrane Transport Chloride Transmembrane Transport	Osteoclast Differentiation Ion Transmembrane Transport
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs
Diseases		Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor	Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS			Major depressive disorder ( 29187746)
Interacting Genes		5 interacting genes: CREB3 LMNA MTDH OSTM1 PACS1	6 interacting genes: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20
Entrez ID		1186	28962
HPRD ID		04103	09628
Ensembl ID		ENSG00000103249	ENSG00000081087
Uniprot IDs		P51798	Q86WC4
PDB IDs
Enriched GO Terms of Interacting Partners?
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