ANTXR2 and LAMB1

Number of citations of the paper that reports this interaction (PubMedID 11683410)
124

Data Source:
BioGRID (pull down)

		ANTXR2	LAMB1
Description		ANTXR cell adhesion molecule 2	laminin subunit beta 1
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-2 Complex Extracellular Space Endoplasmic Reticulum Lumen Laminin Complex Laminin-8 Complex Laminin-10 Complex Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Metal Ion Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Reproductive Process Toxin Transport	Cell Adhesion Animal Organ Morphogenesis Tissue Development Cell Migration Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Extracellular Matrix Organization Positive Regulation Of Cell Migration Neuron Projection Development Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Odontogenesis Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Basement Membrane Assembly
Pathways			Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Infantile systemic hyalinosis and juvenile hyaline fibromatosis
GWAS		Ankylosing spondylitis ( 21743469 20062062) Bipolar disorder (inflammation and infection response interaction) ( 25781172) Carotid plaque burden ( 28282560) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Hand grip strength ( 29691431) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Myopia ( 27182965) Neutrophil percentage of white cells ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	IgG glycosylation ( 23382691) Inflammatory bowel disease ( 28067908) Latent naming speed ( 30995994) Pneumoconiosis in silica exposure ( 24986923) Rapid alternating stimulus test for letters/numbers ( 30995994) Rapid automised naming and rapid alternating stimulus test performance ( 30995994) Rapid automised naming of letters ( 30995994) Ulcerative colitis ( 19915572 28067908 20228799 19122664)
Interacting Genes		10 interacting genes: COL4A2 COL4A3 COL4A4 COL4A5 DDX10 LAMB1 LAMC1 LRP6 RAP1GDS1 SMAD2	12 interacting genes: ACHE ANTXR2 ATXN7 ATXN7L2 CACNA1A COL6A1 ERBIN GFI1B LMNA PRKAR2B PSMC5 UBC
Entrez ID		118429	3912
HPRD ID		07452	01029
Ensembl ID		ENSG00000163297	ENSG00000091136
Uniprot IDs		A4FUA5 J3KPY9 P58335 Q32Q26	G3XAI2 P07942 Q8TAS6
PDB IDs		1SHT 1SHU 1T6B 1TZN	5XAU
Enriched GO Terms of Interacting Partners?
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