FTSJ3 and OAS3

Number of citations of the paper that reports this interaction (PubMedID 21903422)
114

Data Source:
BioGRID (affinity chromatography technology, pull down)

		FTSJ3	OAS3
Description		FtsJ RNA 2'-O-methyltransferase 3	2'-5'-oligoadenylate synthetase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor Preribosome, Small Subunit Precursor	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding RNA Methyltransferase Activity RRNA (uridine-2'-O-)-methyltransferase Activity RRNA (guanine) Methyltransferase Activity	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Enzyme-directed RRNA 2'-O-methylation Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RNA Methylation RRNA Methylation	Nucleobase-containing Compound Metabolic Process Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Body mass index ( 26426971) Chronic lymphocytic leukemia ( 28165464) HDL cholesterol ( 21909109) High density lipoprotein cholesterol levels ( 30718733) Low HDL-cholesterol levels ( 31006500) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239)
Interacting Genes		6 interacting genes: CSNK2A1 EIF2AK2 FANCG MAGEB4 OAS3 SAT1	5 interacting genes: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		117246	4940
HPRD ID		17024	04519
Ensembl ID		ENSG00000108592	ENSG00000111331
Uniprot IDs		Q8IY81	Q9Y6K5
PDB IDs			4S3N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?