CIRBP and BAG5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CIRBP	BAG5
Description		cold inducible RNA binding protein	BAG cochaperone 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex	Nucleus Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Repressor Activity Small Ribosomal Subunit RRNA Binding	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Response To Cold Response To UV Negative Regulation Of Translation Stress Granule Assembly Positive Regulation Of Translation Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Regulation Of RNA Metabolic Process	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)
Interacting Genes		19 interacting genes: APP ATXN1 BAG5 CSNK2A1 ESR1 FBXO7 HNRNPA0 HNRNPK IL7R KHDRBS1 KHDRBS2 LNX1 PRMT1 PRNP RBMX RBMY1A1 RBMY1F SNRPA SRF	18 interacting genes: ANXA3 ATP5MPL BANP CIRBP FAM118B HSPA4 IGHG4 JMJD6 KASH5 LRRK1 PINK1 PRKN SIVA1 SNCA STUB1 THAP1 TP53 TRIM27
Entrez ID		1153	9529
HPRD ID		08375	04862
Ensembl ID		ENSG00000099622	ENSG00000166170
Uniprot IDs		D6W5Y5 K7EPM4 K7EQR7 Q14011 Q53XX5	A0A024R6M6 Q9UL15
PDB IDs		1X5S 5TBX	2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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