MFSD3 and DPAGT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MFSD3	DPAGT1
Description		major facilitator superfamily domain containing 3	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Solute:proton Symporter Activity	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Phospho-N-acetylmuramoyl-pentapeptide-transferase Activity Transferase Activity, Transferring Glycosyl Groups Identical Protein Binding Metal Ion Binding
	Biological Process	Proton Transmembrane Transport	UDP-N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Dolichol Metabolic Process
Pathways			Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		4 interacting genes: APPBP2 DPAGT1 MDFI PCDHGC3	3 interacting genes: LSM8 MFSD3 THTPA
Entrez ID		113655	1798
HPRD ID		14003	01879
Ensembl ID		ENSG00000167700	ENSG00000172269
Uniprot IDs		Q96ES6	A0A024R3H8 Q9H3H5
PDB IDs			5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ
Enriched GO Terms of Interacting Partners?
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