ADCY7 and BUD31

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ADCY7	BUD31
Description		adenylate cyclase 7	BUD31 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Adenylate Cyclase Activity ATP Binding Metal Ion Binding	Protein Binding Nuclear Receptor Transcription Coactivator Activity Nuclear Hormone Receptor Binding
	Biological Process	Regulation Of Adaptive Immune Response Renal Water Homeostasis CAMP Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase A Activity Cellular Response To Lithium Ion Cellular Response To Ethanol Cellular Response To Glucagon Stimulus Negative Regulation Of Cytokine Production Involved In Inflammatory Response	MRNA Splicing, Via Spliceosome Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Androgen Receptor Activity
Pathways		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Ulcerative colitis ( 28067908 28067910)	Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		4 interacting genes: BUD31 PLSCR1 PRKCD XRCC6	7 interacting genes: ADCY7 APP BEND5 CTNNBL1 KRTAP10-3 KRTAP10-7 RELB
Entrez ID		113	8896
HPRD ID		02663	10351
Ensembl ID		ENSG00000121281	ENSG00000106245
Uniprot IDs		B3KSJ0 F5H4D1 P51828 Q86YI0	P41223
PDB IDs			4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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