PMF1 and CRMP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PMF1	CRMP1
Description		polyamine modulated factor 1	collapsin response mediator protein 1
Image
GO Annotations	Cellular Component	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Nucleoplasm Transcription Factor Complex Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon
	Molecular Function	Transcription Coactivator Activity Protein Binding Leucine Zipper Domain Binding	Dihydropyrimidinase Activity Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Filamin Binding Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase II Cell Cycle Chromosome Segregation Cell Division Positive Regulation Of Nucleic Acid-templated Transcription	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 30604766) Intracerebral hemorrhage ( 24656865) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Longevity (age >99th survival percentile) ( 31413261) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Stroke ( 29531354) White matter hyperintensity burden ( 25663218)	Blood trace element (Zn levels) ( 23720494) Metabolite levels ( 23823483)
Interacting Genes		17 interacting genes: CEP126 COPS6 COPS7A COPS7B CRMP1 DSN1 GDF9 GIT1 HSP90AA1 KDM1A MED31 MIS12 NFE2L2 PTN SUGT1 TCP10L USHBP1	77 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24
Entrez ID		11243	1400
HPRD ID		11441	03913
Ensembl ID		ENSG00000160783	ENSG00000072832
Uniprot IDs		Q6P1K2	B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1
PDB IDs		5LSJ 5LSK	4B3Z
Enriched GO Terms of Interacting Partners?
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