EGLN2 and TENT5A

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EGLN2	TENT5A
Description		egl-9 family hypoxia inducible factor 2	terminal nucleotidyltransferase 5A
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm
	Molecular Function	Protein Binding Ferrous Iron Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Oxygen Sensor Activity L-ascorbic Acid Binding Peptidyl-proline 4-dioxygenase Activity	RNA Binding Protein Binding RNA Adenylyltransferase Activity
	Biological Process	Regulation Of Cell Growth Response To Hypoxia Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Intracellular Estrogen Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Cell Redox Homeostasis Positive Regulation Of Protein Catabolic Process Oxidation-reduction Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia	Response To Bacterium
Pathways		Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs		Vitamin C Roxadustat
Diseases
GWAS		Chronic obstructive pulmonary disease ( 22080838) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) nicotine metabolite ratio in current smokers ( 28921760) Parental longevity (father's attained age) ( 29227965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smoking behavior ( 20418890) Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes		11 interacting genes: A2M CDK2 EPAS1 HIF1A HIF3A MFHAS1 MOB4 PRKCA SPOP SRPK2 TENT5A	18 interacting genes: ATXN1 BAG6 BCCIP CD93 COL4A2 DYNC1H1 EGLN2 HDLBP HTRA1 KEAP1 NR2F2 PSG3 RIN3 RNF14 SPINT1 TBX4 TNS2 ZFYVE9
Entrez ID		112398	55603
HPRD ID		06970	13311
Ensembl ID		ENSG00000269858	ENSG00000112773
Uniprot IDs		A0A024R0R2 Q96KS0	Q96IP4
PDB IDs		5V1B
Enriched GO Terms of Interacting Partners?
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