AKAP10 and RALA

		AKAP10	RALA
Description		A-kinase anchoring protein 10	RAS like proto-oncogene A
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GO Annotations	Cellular Component	Mitochondrion Cytosol Plasma Membrane Protein-containing Complex	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Protein Kinase A Binding	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Signal Transduction Blood Coagulation Protein Localization	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways		Factors involved in megakaryocyte development and platelet production	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Body mass index ( 29273807) Mean platelet volume ( 27863252) Platelet count ( 22139419 27863252) Schizophrenia ( 28991256) Strenuous sports or other exercises ( 29899525)
Interacting Genes		8 interacting genes: IKZF3 PDZK1 PRKAR1A PRKAR2A PRKAR2B RALA SASH1 SLC9A3R1	36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		11216	5898
HPRD ID		05259	01549
Ensembl ID		ENSG00000108599	ENSG00000006451
Uniprot IDs		A0A0S2Z4Z7 E7EMD6 O43572	P11233
PDB IDs		3IM4 3TMH	1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?
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