MAP4K5 and ZNF440

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		MAP4K5	ZNF440
Description		mitogen-activated protein kinase kinase kinase kinase 5	zinc finger protein 440
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity	DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	MAPK Cascade Activation Of MAPKKK Activity Protein Phosphorylation Activation Of JUN Kinase Activity Regulation Of Mitotic Cell Cycle Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Intracellular Signal Transduction	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Cognitive performance ( 20125193) Dupuytren's disease ( 28886342) Heel bone mineral density ( 30598549) Lupus nephritis in systemic lupus erythematosus ( 24925725) Periodontal disease-related phenotype (Socransky) ( 24347629)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		13 interacting genes: ABL1 BCR COPS5 CRK CRKL GRB2 HCK NEDD4 SETDB1 SMURF1 TANK TRAF2 ZNF440	14 interacting genes: CCNDBP1 KRTAP10-1 KRTAP10-9 KRTAP4-12 LMNA MAP4K5 MDFI MID2 MTUS2 NOTCH2NLA PAX9 PJA1 TRAF1 XBP1
Entrez ID		11183	126070
HPRD ID		05374	11718
Ensembl ID		ENSG00000012983	ENSG00000171295
Uniprot IDs		B3KWC4 Q9Y4K4	Q8IYI8
PDB IDs
Enriched GO Terms of Interacting Partners?
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