CHGB and PRAG1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)

		CHGB	PRAG1
Description		chromogranin B	PEAK1 related, kinase-activating pseudokinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule	Nucleus Cytoplasm Focal Adhesion
	Molecular Function	Hormone Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Phosphorylation Regulation Of Cell Shape Regulation Of Notch Signaling Pathway Negative Regulation Of Neuron Projection Development Cell Migration Positive Regulation Of Rho Protein Signal Transduction Regulation Of Cell Motility
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)	Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31152163) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	3 interacting genes: CHGB PSAP UBE3A
Entrez ID		1114	157285
HPRD ID		07512	19497
Ensembl ID		ENSG00000089199	ENSG00000275342
Uniprot IDs		P05060	Q86YV5
PDB IDs			5VE6
Enriched GO Terms of Interacting Partners?
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