ZWINT and ZW10

Number of citations of the paper that reports this interaction (PubMedID 15824131)
110

Data Source:
HPRD (in vivo, in vitro)

		ZWINT	ZW10
Description		ZW10 interacting kinetochore protein	zw10 kinetochore protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cell Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cell Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex
	Molecular Function	Protein Binding Protein N-terminus Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Cell Division Establishment Of Localization In Cell	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447)	Parental longevity (father's attained age) ( 29227965)
Interacting Genes		9 interacting genes: APP CLU DSN1 LIG4 MAFB MIS12 NDC80 PHAX ZW10	7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT
Entrez ID		11130	9183
HPRD ID		18366	04902
Ensembl ID		ENSG00000122952	ENSG00000086827
Uniprot IDs		O95229	O43264
PDB IDs
Enriched GO Terms of Interacting Partners?
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