IMMT and PPOX

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IMMT	PPOX
Description		inner membrane mitochondrial protein	protoporphyrinogen oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane MICOS Complex	Mitochondrion Mitochondrial Intermembrane Space Intrinsic Component Of Mitochondrial Inner Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	RNA Binding Protein Binding	Oxygen-dependent Protoporphyrinogen Oxidase Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Cristae Formation Mitochondrial Calcium Ion Homeostasis Mitochondrion Morphogenesis	Porphyrin-containing Compound Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Response To Drug Oxidation-reduction Process
Pathways		Cristae formation	Heme biosynthesis
Drugs
Diseases			Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS		Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		59 interacting genes: AKTIP ALB ANTKMT ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD KDM1A KIF22 KPNA2 LRIF1 MRPL44 MRPS5 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PDE4DIP PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4	4 interacting genes: COPS5 HAP1 HNRNPD IMMT
Entrez ID		10989	5498
HPRD ID		02658	02953
Ensembl ID		ENSG00000132305	ENSG00000143224
Uniprot IDs		Q16891	P50336
PDB IDs			3NKS 4IVM 4IVO
Enriched GO Terms of Interacting Partners?
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