OS9 and PGD

		OS9	PGD
Description		OS9 endoplasmic reticulum lectin	phosphogluconate dehydrogenase
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GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Catabolic Process Oxidation-reduction Process
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)	Pentose phosphate pathway
Drugs			Gadopentetate dimeglumine Dacarbazine Ketotifen 6-phospho-D-gluconic acid Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Hepatocellular carcinoma ( 20676096) Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: ACP1 ACVR1B CPNE6 CREB3 DCSTAMP EGLN1 EGLN3 EIF6 FAIM2 FOXM1 GLS2 HIF1A HSP90B1 LINC00839 MEP1B P3H3 PGD PTH RBX1 SCN8A SLC22A1 SMAD2 SNRPD2 SREBF2 TRPV4 UVRAG ZNF512B	6 interacting genes: ALG5 CDK4 GBE1 LSM8 OS9 TERF1
Entrez ID		10956	5226
HPRD ID		17804	01391
Ensembl ID		ENSG00000135506	ENSG00000142657
Uniprot IDs		Q13438	B4E2U0 P52209
PDB IDs		3AIH	2JKV 4GWG 4GWK 5UQ9
Enriched GO Terms of Interacting Partners?
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