NOXA1 and NOX1

Number of citations of the paper that reports this interaction (PubMedID 16329988)
6

Data Source:
BioGRID (pull down)

		NOXA1	NOX1
Description		NADPH oxidase activator 1	NADPH oxidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Cell Early Endosome Plasma Membrane Cell Junction NADPH Oxidase Complex Invadopodium Membrane
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Rac GTPase Binding	Voltage-gated Ion Channel Activity Protein Binding Superoxide-generating NADPH Oxidase Activity Metal Ion Binding Rac GTPase Binding NADP Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin NADP Metabolic Process Defense Response Inflammatory Response Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Cell Proliferation Positive Regulation Of Vascular Endothelial Growth Factor Production Cell Migration Extracellular Matrix Organization Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Superoxide Anion Generation Hydrogen Peroxide Metabolic Process Positive Regulation Of Integrin Biosynthetic Process Respiratory Burst Positive Regulation Of JNK Cascade Positive Regulation Of Smooth Muscle Cell Proliferation Intracellular PH Elevation Oxidation-reduction Process Cellular Response To Hyperoxia Oxygen Metabolic Process Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Stress Response To Acidic PH
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs			Oxygen
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		14 interacting genes: CACNA1A EP300 FAT1 MAPK1 MAPK11 NCF1 NOX1 NOXO1 PRKACA PRKCA PRKCG RAC1 RAC2 RIMBP3	4 interacting genes: ARHGEF7 CYBA NOXA1 NOXO1
Entrez ID		10811	27035
HPRD ID		17644	02203
Ensembl ID		ENSG00000188747	ENSG00000007952
Uniprot IDs		Q86UR1	A6NGA6 Q1ZYL4 Q9Y5S8
PDB IDs
Enriched GO Terms of Interacting Partners?
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