AHCYL1 and ZNF165

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AHCYL1	ZNF165
Description		adenosylhomocysteinase like 1	zinc finger protein 165
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Extracellular Exosome	Nucleus
	Molecular Function	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Regulation Of Cardiac Conduction	Myelination Negative Regulation Of Transcription, DNA-templated
Pathways		PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Height ( 31562340)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Estimated glomerular filtration rate ( 31451708) Hepcidin/ferritin ratio ( 27846281) Moderate to vigorous physical activity levels ( 29899525) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		17 interacting genes: BID CDKN2C DACH1 GEM HGS ITPR1 LRRK2 MEOX2 MFHAS1 PPL PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 ZNF165	22 interacting genes: AHCYL1 CCDC130 CCDC85B DVL2 ELOA2 EMD EWSR1 FAM124A GPATCH2L KAT7 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 MID2 PDLIM7 SCAND1 SUV39H1 ZKSCAN8 ZNF24 ZNF250 ZNF446
Entrez ID		10768	7718
HPRD ID		07613	02903
Ensembl ID		ENSG00000168710	ENSG00000197279
Uniprot IDs		A0A024R0A8 O43865	P49910 Q53Z40
PDB IDs		3MTG
Enriched GO Terms of Interacting Partners?
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