GIPC1 and RGS19

Number of citations of the paper that reports this interaction (PubMedID 9770488)
64

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		GIPC1	RGS19
Description		GIPC PDZ domain containing family member 1	regulator of G protein signaling 19
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Brush Border Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Endocytic Vesicle Cytoplasmic Vesicle Dendritic Spine Dendritic Shaft Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Golgi Apparatus Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle Membrane Raft
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Myosin Binding PDZ Domain Binding Identical Protein Binding Cadherin Binding	G-protein Alpha-subunit Binding GTPase Activity Protein Binding
	Biological Process	Protein Targeting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Positive Regulation Of Melanin Biosynthetic Process Regulation Of Synaptic Plasticity Cellular Response To Interleukin-7 Regulation Of Synaptic Vesicle Exocytosis	Autophagy G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Negative Regulation Of Signal Transduction Response To Ethanol
Pathways			G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Kidney stones ( 31729369)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Mean corpuscular volume ( 27863252) Systolic blood pressure ( 30578418)
Interacting Genes		37 interacting genes: ACTN1 ADRB1 ARHGEF12 BRD4 CARD10 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KIF1B LHCGR LPAR1 LPAR2 LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SH3BP4 SLC2A1 TGFBR3 TPBG TYRP1 ZFPM1 ZNF408	15 interacting genes: CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ MAPK1 MAPK6 OPRL1 OSTM1 PRKCA TGFBR1
Entrez ID		10755	10287
HPRD ID		05462	05461
Ensembl ID		ENSG00000123159	ENSG00000171700
Uniprot IDs		A0A024R7I0 A0A024R7I1 A8K2I7 O14908	B4DP94 P49795
PDB IDs			1CMZ
Enriched GO Terms of Interacting Partners?
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