GRAP and KHDRBS1

Number of citations of the paper that reports this interaction (PubMedID 8995379)
33

Data Source:
HPRD (in vivo, in vitro)

		GRAP	KHDRBS1
Description		GRB2 related adaptor protein	KH RNA binding domain containing, signal transduction associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Cell Junction Presynapse	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Protein-containing Complex Grb2-Sos Complex
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling Sensory Perception Of Sound Positive Regulation Of Signal Transduction	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Cell Surface Receptor Signaling Pathway Spermatogenesis Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Signaling by SCF-KIT	PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Copper levels ( 26025379)	Body mass index ( 26426971)
Interacting Genes		14 interacting genes: ARHGAP32 EPOR FASLG FYN GAB2 KHDRBS1 KIT LAT LCK PLCG1 RBPMS SHC1 SOS1 TRIM21	109 interacting genes: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK CBL CD2AP CDK1 CIRBP CLK1 CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITPRID2 ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SRPK2 STAT3 STUB1 TBL1X TJP1 TSPOAP1 TUBB3 UBA52 UBASH3B UBC VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		10750	10657
HPRD ID		05062	03926
Ensembl ID		ENSG00000154016	ENSG00000121774
Uniprot IDs		I3L2P9 Q13588	Q07666
PDB IDs			2XA6 3QHE
Enriched GO Terms of Interacting Partners?
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