AP4B1 and BUB1

Number of citations of the paper that reports this interaction (PubMedID 12419313)
12

Data Source:
HPRD (two hybrid)

		AP4B1	BUB1
Description		adaptor related protein complex 4 subunit beta 1	BUB1 mitotic checkpoint serine/threonine kinase
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GO Annotations	Cellular Component	Trans-Golgi Network Cytosol Extrinsic Component Of Membrane AP-4 Adaptor Complex Clathrin Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleoplasm Cytosol Membrane
	Molecular Function	Protein Binding Clathrin Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Targeting Protein Localization Vesicle-mediated Transport	Protein Phosphorylation Apoptotic Process Regulation Of Sister Chromatid Cohesion Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Cerebral palsy
GWAS		Alopecia areata ( 25608926) Breast cancer ( 23535729) Crohn's disease ( 28067908) Obesity-related traits ( 23251661) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
Interacting Genes		5 interacting genes: AP4E1 AP4M1 BUB1 BUB1B ZNF576	18 interacting genes: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB3 CDC20 CDK1 CRK EIF4EBP1 FBXO7 HDAC1 KNL1 PLK1 RAE1 RDH12 SVIL
Entrez ID		10717	699
HPRD ID		06259	03907
Ensembl ID		ENSG00000134262	ENSG00000169679
Uniprot IDs		A0A024R0J5 B1ALD0 B3KSJ4 B4DTG3 Q9Y6B7	B4DYG2 O43683
PDB IDs		2MJ7	2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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