POLR3C and GTF3C4

Number of citations of the paper that reports this interaction (PubMedID 10523658)
35

Data Source:
HPRD (in vitro, in vivo)

		POLR3C	GTF3C4
Description		RNA polymerase III subunit C	general transcription factor IIIC subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	Single-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Positive Regulation Of Catalytic Activity
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: APP CEP63 GTF3C4 PNMA5 ROCK1 ROPN1 TNR TRIM27	13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F PRRC2B TBP
Entrez ID		10623	9329
HPRD ID		17880	11998
Ensembl ID		ENSG00000186141	ENSG00000125484
Uniprot IDs		Q9BUI4	B3KNH2 Q9UKN8
PDB IDs		2XUB 2XV4 5AFQ
Enriched GO Terms of Interacting Partners?
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