HOXB13 and HOXD4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXB13	HOXD4
Description		homeobox B13	homeobox D4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Cell Junction
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Methyl-CpG Binding Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Activating Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Epidermis Development Response To Wounding Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development	Skeletal System Development Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Prostate cancer ( 23104005 23535732)	Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		8 interacting genes: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 RAB5C ZNF490	19 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18
Entrez ID		10481	3233
HPRD ID		05210	00864
Ensembl ID		ENSG00000159184	ENSG00000170166
Uniprot IDs		Q4KR72 Q92826	P09016
PDB IDs		2CRA 5EDN 5EEA 5EF6 5EG0 5EGO 5NO6
Enriched GO Terms of Interacting Partners?
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