ZNHIT1 and GRB7

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		ZNHIT1	GRB7
Description		zinc finger HIT-type containing 1	growth factor receptor bound protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm	Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Stress Granule Cell Projection
	Molecular Function	Protein Binding Nucleosome Binding Histone Deacetylase Binding Metal Ion Binding	RNA Binding SH3/SH2 Adaptor Activity Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Regulation Of Histone Deacetylation Histone Exchange	Epidermal Growth Factor Receptor Signaling Pathway Axon Guidance Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Translation Positive Regulation Of Cell Migration Stress Granule Assembly ERBB2 Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Leukocyte Migration
Pathways			GRB7 events in ERBB2 signaling Signaling by SCF-KIT Downstream signal transduction Tie2 Signaling RET signaling
Drugs
Diseases
GWAS			Asthma ( 31619474 28461288) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Height ( 31562340) Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 26502338) Ulcerative colitis ( 28067908 20228799)
Interacting Genes		13 interacting genes: AKAP8 CSNK2B DAPP1 GRB7 HINFP KRTAP10-7 MAPK11 MAPK14 PMPCB RIPK1 SH2D1A TNIP1 TP53	42 interacting genes: A1BG AGAP1 ATP5F1B CALM1 CAV1 CPNE6 DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 FGB FLAD1 GIGYF1 GIGYF2 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MSH2 PDGFRB PDHB PHAX PKM PTK2 RET RND1 RPS2 SETDB1 SHC1 TEK TLE1 TMSB4X TRIM36 ZBTB16 ZNHIT1
Entrez ID		10467	2886
HPRD ID		15892	03311
Ensembl ID		ENSG00000106400	ENSG00000141738
Uniprot IDs		O43257	A0A0S2Z4F6 Q14451
PDB IDs			1MW4 1WGR 2L4K 2QMS 3PQZ 4WWQ 4X6S 5D0J 5EEL 5EEQ 5TYI 5U06 5U1Q
Enriched GO Terms of Interacting Partners?
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