PPIH and PRPF18

Number of citations of the paper that reports this interaction (PubMedID 11823439)
38

Data Source:
HPRD (in vitro, in vivo)

		PPIH	PRPF18
Description		peptidylprolyl isomerase H	pre-mRNA processing factor 18
Image
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Nucleus Spliceosomal Complex U5 SnRNP Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Post-spliceosomal Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding Unfolded Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Angiogenesis Protein Folding Protein Refolding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA Processing RNA Splicing Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Pathways		mRNA Splicing - Major Pathway
Drugs		L-Proline
Diseases
GWAS			Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) Craniofacial microsomia ( 26853712) Lupus nephritis in systemic lupus erythematosus ( 24925725) Post bronchodilator FEV1/FVC ratio ( 26634245) Skin pigmentation ( 28300201)
Interacting Genes		8 interacting genes: BAG2 LNX2 N4BP2L2 PRPF18 PRPF31 PRPF4 SNU13 XIAP	2 interacting genes: PPIH RHOU
Entrez ID		10465	8559
HPRD ID		12084	05407
Ensembl ID		ENSG00000171960	ENSG00000165630
Uniprot IDs		O43447 Q6FH36	Q99633
PDB IDs		1MZW 1QOI 5O9Z 6AHD	2DK4
Enriched GO Terms of Interacting Partners?
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