PCGF3 and BCOR

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		PCGF3	BCOR
Description		polycomb group ring finger 3	BCL6 corepressor
Image		No pdb structure
GO Annotations	Cellular Component	X Chromosome Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus Nucleoplasm BCOR Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Histone H2A-K119 Monoubiquitination Inactivation Of X Chromosome By Genetic Imprinting	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K36 Methylation Blastocyst Hatching Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		General cognitive ability ( 29844566) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 22443383) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30297969) White blood cell count ( 27863252)	Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Venous thromboembolism ( 31676865)
Interacting Genes		10 interacting genes: BCOR BCORL1 BMI1 CBX6 DZIP3 HNRNPK PHC2 TRIM9 UBE2C UBE2D3	17 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF1 PCGF3 SP1 UBTD1 USP7
Entrez ID		10336	54880
HPRD ID		11515	06458
Ensembl ID		ENSG00000185619	ENSG00000183337
Uniprot IDs		B3KQ06 B3KWT8 B4DTN5 Q3KNV8	Q6W2J9
PDB IDs			2N1L 3BIM 4HPL 6B7G
Enriched GO Terms of Interacting Partners?
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