KLHL41 and IFRD1

Number of citations of the paper that reports this interaction (PubMedID 30986853)
2

Data Source:
BioGRID (two hybrid)

		KLHL41	IFRD1
Description		kelch like family member 41	interferon related developmental regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Regulation Of Lateral Pseudopodium Assembly Skeletal Muscle Cell Differentiation Post-translational Protein Modification Sarcomere Organization Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Myoblast Fate Determination Striated Muscle Tissue Development Negative Regulation Of Axon Extension Muscle Cell Differentiation Skeletal Muscle Tissue Regeneration Negative Regulation Of Collateral Sprouting
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (age of onset) ( 22959728) Dental caries (decayed, missing and filled teeth) ( 31533690) Mortality in heart failure ( 20400778) Osteoarthritis (hip) ( 23989986)
Interacting Genes		7 interacting genes: CENPF IFRD1 NEB NRAP RBM4 RCHY1 SLC2A4	6 interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 RIT1
Entrez ID		10324	3475
HPRD ID		07610	04612
Ensembl ID		ENSG00000239474	ENSG00000006652
Uniprot IDs		O60662	A4D0U1 O00458
PDB IDs
Enriched GO Terms of Interacting Partners?
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