DLEU1 and ABCD4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLEU1	ABCD4
Description		deleted in lymphocytic leukemia 1	ATP binding cassette subfamily D member 4
Image		No pdb structure
GO Annotations	Cellular Component		Lysosomal Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane ATP-binding Cassette (ABC) Transporter Complex
	Molecular Function		ATP Binding ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process		Cobalamin Metabolic Process Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor
Pathways			Cobalamin (Cbl, vitamin B12) transport and metabolism Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ)
Drugs
Diseases
GWAS		Adiponectin levels ( 26299439) Adiponectin levels (BMI-adjusted) ( 26299439) Aluminium levels ( 26025379) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163) Circulating odd-numbered chain saturated fatty acid levels (C19:0) ( 29738550) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 31562340 31217584) Hematocrit ( 29403010) Hemoglobin ( 29403010) Hip circumference adjusted for BMI ( 28552196) Lipoprotein (a) levels ( 30108283) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244 21833088 27386562) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376) Plasma anti-thyroid peroxidase levels ( 29678681) Primary biliary cholangitis ( 26394269) Prostate-specific antigen levels ( 28139693) Triglycerides ( 30275531) Tumor necrosis factor alpha levels ( 31217265) Type 2 diabetes ( 30054458 30297969) Urinary albumin-to-creatinine ratio ( 31630189) Urinary magnesium excretion ( 31993563) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196) Weight ( 28552196)
Interacting Genes		20 interacting genes: ABCD4 ABCF3 ARL8B CCDC90B CEP126 COPS6 EEF1A1 EEF1G GDF9 GOPC KAT5 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A	5 interacting genes: DLEU1 HSPB2 PEA15 SARAF XRCC6
Entrez ID		10301	5826
HPRD ID		16150	04446
Ensembl ID		ENSG00000176124	ENSG00000119688
Uniprot IDs			A0A024R6B9 O14678
PDB IDs			6JBJ
Enriched GO Terms of Interacting Partners?
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