SIGMAR1 and PDZD11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SIGMAR1	PDZD11
Description		sigma non-opioid intracellular receptor 1	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Plasma Membrane Postsynaptic Density Integral Component Of Membrane Cell Junction Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	Opioid Receptor Activity Protein Binding Drug Binding	Protein Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane
Pathways			Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Amitriptyline Remoxipride Dextromethorphan Nortriptyline Pentazocine Cocaine Dimethyltryptamine Prasterone Phencyclidine Captodiame
Diseases
GWAS
Interacting Genes		13 interacting genes: ANK2 DCAF12 DNAJB5 GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP	16 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MYO1F NLGN3 PLEKHA5 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3
Entrez ID		10280	51248
HPRD ID		03580	06622
Ensembl ID		ENSG00000147955	ENSG00000120509
Uniprot IDs		A2A3U5 B4DR71 Q99720	Q5EBL8
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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