TRIM28 and PFDN5

Number of citations of the paper that reports this interaction (PubMedID 11585818)
31

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TRIM28	PFDN5
Description		tripartite motif containing 28	prefoldin subunit 5
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Protein-containing Complex RNA Polymerase II Transcription Factor Complex	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Kinase Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding Krueppel-associated Box Domain Binding Sequence-specific DNA Binding Chromo Shadow Domain Binding Promoter-specific Chromatin Binding	Transcription Corepressor Activity Protein Binding Unfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Epithelial To Mesenchymal Transition DNA Repair Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter Ras Protein Signal Transduction Embryo Implantation Viral Process Protein Ubiquitination Protein Sumoylation Positive Regulation Of Protein Import Into Nucleus DNA Methylation Involved In Embryo Development Positive Regulation Of DNA Binding Innate Immune Response Positive Regulation Of DNA Repair Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Convergent Extension Involved In Axis Elongation Embryonic Placenta Morphogenesis Positive Regulation Of Methylation-dependent Chromatin Silencing Negative Regulation Of DNA Demethylation Negative Regulation Of Viral Release From Host Cell Regulation Of Genetic Imprinting	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Generic Transcription Pathway SUMOylation of transcription cofactors HCMV Early Events	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Interacting Genes		70 interacting genes: CBX1 CBX3 CBX5 CDC34 CDCA4 CDKN2A CEBPB CHAF1A CHD3 ESR1 EZH2 FBP1 FES HDAC10 HTRA2 IRF1 IRF7 LYN MAGEA2 MAGEA2B MAGEA6 MAGED1 MAPKAPK2 MYB NPM1 NR3C1 NR4A1 NR4A3 NSMCE3 PFDN5 PPP2CA PPP4C RNF4 SERTAD1 SERTAD2 SETDB1 SIN3A SIRT1 SKI SMARCAD1 SPG7 STAT3 SUMO2 TP73 TRIM24 TWIST1 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U VHL VIM YWHAQ ZNF10 ZNF133 ZNF140 ZNF197 ZNF354A ZNF382 ZNF420 ZNF496 ZNF689 ZNF74	13 interacting genes: BRMS1 CALCOCO2 GLRX3 IKBKG IKZF3 ITSN1 MYC PFDN6 PSME3 TP73 TRIM28 TUBA1B TUBA3C
Entrez ID		10155	5204
HPRD ID		03445	05359
Ensembl ID		ENSG00000130726	ENSG00000123349
Uniprot IDs		Q13263	Q99471
PDB IDs		1FP0 2RO1 2YVR 6H3A 6I9H 6QAJ 6QU1	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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