PQBP1 and HNRNPH2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		PQBP1	HNRNPH2
Description		polyglutamine binding protein 1	heterogeneous nuclear ribonucleoprotein H2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule	Nucleus Nucleoplasm Cytosol Postsynaptic Density Membrane Ribonucleoprotein Complex
	Molecular Function	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Ribonucleoprotein Complex Binding	RNA Binding Protein Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Transcription, DNA-templated Neuron Projection Development Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Innate Immune Response Regulation Of Dendrite Morphogenesis Defense Response To Virus Cellular Response To Exogenous DsRNA Positive Regulation Of Nucleic Acid-templated Transcription	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation
GWAS
Interacting Genes		24 interacting genes: APBB1 APP AQR ATXN1 CLTB EEF1A1 ERG28 ESR1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77	22 interacting genes: DDX5 GLA HNRNPA0 HNRNPUL1 ILF3 MSI2 PQBP1 PRMT6 PRPF31 PRPF8 QKI RACK1 RAD21 RBFOX2 RBM10 RBM39 RBM4 SF1 SNRPC TEKT1 TLE5 WDR83
Entrez ID		10084	3188
HPRD ID		02354	03022
Ensembl ID		ENSG00000102103	ENSG00000126945
Uniprot IDs		A0A0S2Z4V5 O60828	A0A384MDT2 P55795
PDB IDs		4BWQ 4BWS 4CDO	1WEZ 1WG5 6DG1
Enriched GO Terms of Interacting Partners?
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