DNM1L and MFF

Number of citations of the paper that reports this interaction (PubMedID 23530241)
76

Data Source:
BioGRID (pull down)

		DNM1L	MFF
Description		dynamin 1 like	mitochondrial fission factor
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Microtubule Brush Border Clathrin-coated Pit Membrane Cell Junction Synaptic Vesicle Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Presynaptic Endocytic Zone Membrane Mitochondrion-derived Vesicle	Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Cell Junction Integral Component Of Mitochondrial Membrane Protein-containing Complex
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Microtubule Binding Lipid Binding Rab GTPase Binding Clathrin Binding GTP-dependent Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding BH2 Domain Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Calcium Ion Transport Mitochondrion Organization Endoplasmic Reticulum Organization Apoptotic Mitochondrial Changes Regulation Of Gene Expression Negative Regulation Of Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Synaptic Vesicle Recycling Via Endosome Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Mitochondrial Fragmentation Involved In Apoptotic Process Organelle Fission Intracellular Distribution Of Mitochondria Synaptic Vesicle Endocytosis Rhythmic Process Positive Regulation Of Protein Secretion Protein Complex Oligomerization Heart Contraction Positive Regulation Of Dendritic Spine Morphogenesis Membrane Fusion Protein-containing Complex Assembly Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Cellular Response To Oxygen-glucose Deprivation Execution Phase Of Apoptosis Regulation Of Peroxisome Organization Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Autophagy Of Mitochondrion Regulation Of ATP Metabolic Process Cellular Response To Thapsigargin Regulation Of Ubiquitin Protein Ligase Activity Response To Flavonoid Response To Hypobaric Hypoxia Positive Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Targeting To Membrane Regulation Of Peroxisome Organization
Pathways		Apoptotic execution phase
Drugs
Diseases
GWAS			Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)
Interacting Genes		20 interacting genes: FIS1 FZR1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF1 MIEF2 MUL1 PINK1 PRKN RRM2 SCG3 SENP3 SH3GL1 SIRT3 SUMO2 VIM ZBTB24	2 interacting genes: DNM1L MTNR1B
Entrez ID		10059	56947
HPRD ID		04833	16653
Ensembl ID		ENSG00000087470	ENSG00000168958
Uniprot IDs		B4DYR6 O00429	A0A0A0MS29 A1MAC2 Q9GZY8
PDB IDs		3W6N 3W6O 3W6P 4BEJ 4H1U 4H1V 5WP9
Enriched GO Terms of Interacting Partners?
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