UBA2 and SERBP1

Number of citations of the paper that reports this interaction (PubMedID 16679534)
12

Data Source:
HPRD (in vivo, two hybrid)

		UBA2	SERBP1
Description		ubiquitin like modifier activating enzyme 2	SERPINE1 mRNA binding protein 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity	RNA Binding MRNA 3'-UTR Binding Protein Binding SUMO Binding Cadherin Binding
	Biological Process	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation	PML Body Organization Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS			Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)
Interacting Genes		14 interacting genes: BRIX1 CHEK1 ETV4 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBE2I	20 interacting genes: - APP CHD3 CSNK2A1 DAXX ESR1 FBXO25 FXYD3 KAT2B PIAS1 PIAS3 PIAS4 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM
Entrez ID		10054	26135
HPRD ID		11658	09570
Ensembl ID		ENSG00000126261	ENSG00000142864
Uniprot IDs		Q9UBT2	Q5VU21 Q63HR1 Q8NC51
PDB IDs		1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ	4V6X
Enriched GO Terms of Interacting Partners?
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