CDH2 and ARVCF

Number of citations of the paper that reports this interaction (PubMedID 11058098)
14

Data Source:
HPRD (in vitro, in vivo)

		CDH2	ARVCF
Description		cadherin 2	ARVCF delta catenin family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Fascia Adherens Focal Adhesion Cell Surface Postsynaptic Density Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Cell Junction Cortical Actin Cytoskeleton Sarcolemma Neuron Projection Plasma Membrane Raft Apical Part Of Cell Synapse Collagen-containing Extracellular Matrix Integral Component Of Presynaptic Active Zone Membrane Integral Component Of Postsynaptic Specialization Membrane	Intracellular Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction
	Molecular Function	Calcium Ion Binding Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Protein Kinase Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding Cadherin Binding	Protein Binding Cadherin Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organism Development Synapse Assembly Brain Development Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cerebral Cortex Development Adherens Junction Organization Positive Regulation Of MAPK Cascade Post-translational Protein Modification Cellular Protein Metabolic Process Cell-cell Adhesion Mediated By Cadherin Blood Vessel Morphogenesis Brain Morphogenesis Homeostasis Of Number Of Cells Regulation Of Axonogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Regulation Of Synaptic Transmission, Glutamatergic Radial Glial Cell Differentiation Neuroepithelial Cell Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Protein Localization To Plasma Membrane Negative Regulation Of Canonical Wnt Signaling Pathway Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Neuronal Stem Cell Population Maintenance Cell-cell Adhesion Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Synaptic Vesicle Clustering	Cell-cell Junction Assembly Cell Adhesion Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell-cell Adhesion
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Adherens junctions interactions Myogenesis Myogenesis Post-translational protein phosphorylation
Drugs
Diseases			Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS		Breast cancer ( 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 24023788) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Periodontal disease-related phenotype (Socransky) ( 24347629) Response to hepatitis B vaccine ( 29534301) Resting heart rate ( 27798624) Temperament (bipolar disorder) ( 22365631) Type 2 diabetes ( 31049640) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) vWF and FVIII levels ( 21810271)	Central corneal thickness ( 29760442) Lymphocyte counts ( 27863252) Medication use (antihypertensives) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Monocyte count ( 27863252) Platelet count ( 22139419 27863252) Pulse pressure ( 28135244 27841878 28739976 30487518 30578418) Systolic blood pressure ( 27841878 30487518 30578418) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) White blood cell count ( 27863252)
Interacting Genes		23 interacting genes: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1 UBC	6 interacting genes: CDH1 CDH15 CDH2 ERBIN LNX1 TJP1
Entrez ID		1000	421
HPRD ID		00226	03778
Ensembl ID		ENSG00000170558	ENSG00000099889
Uniprot IDs		A0A024RC42 P19022	C9JJX6 E9PDC3 O00192
PDB IDs
Enriched GO Terms of Interacting Partners?
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