SNAI2

Description		snail family transcriptional repressor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding E-box Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Epithelial To Mesenchymal Transition Aortic Valve Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Cell Migration Involved In Endocardial Cushion Formation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Notch Signaling Pathway Sensory Perception Of Sound Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Vitamin D Biosynthetic Process Neural Crest Cell Development Positive Regulation Of Cell Migration Negative Regulation Of Chondrocyte Differentiation Regulation Of Chemokine Production Negative Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Histone Acetylation Desmosome Disassembly Pigmentation Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Fat Cell Differentiation Regulation Of Osteoblast Differentiation White Fat Cell Differentiation Roof Of Mouth Development Epithelium Development Cartilage Morphogenesis Regulation Of Branching Involved In Salivary Gland Morphogenesis Notch Signaling Involved In Heart Development Negative Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Ionizing Radiation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Stem Cell Proliferation Regulation Of Bicellular Tight Junction Assembly Negative Regulation Of Anoikis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases		Piebaldism Waardenburg syndrome (WS)
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252)
Interacting Genes		8 interacting genes: APP PIAS1 PIAS2 PIAS3 PIAS4 SAT1 TRIM23 UBE2I
Entrez ID		6591
HPRD ID		03689
Ensembl ID		ENSG00000019549
Uniprot IDs		O43623
PDB IDs
Enriched GO Terms of Interacting Partners?
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