PDIA6

Description		protein disulfide isomerase family A member 6
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GO Annotations	Cellular Component	Extracellular Space Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Endoplasmic Reticulum Chaperone Complex Melanosome Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Peptide Disulfide Oxidoreductase Activity
	Biological Process	Protein Folding IRE1-mediated Unfolded Protein Response Post-translational Protein Modification Cellular Protein Metabolic Process Cell Redox Homeostasis Oxidation-reduction Process
Pathways		XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
Interacting Genes		14 interacting genes: ATP13A2 CASP8 CEP250 CLN8 CSNK2A1 LGALS9 MTNR1A MTNR1B NPC2 SLC2A4 SUMO4 TRIM14 UBE3A VKORC1
Entrez ID		10130
HPRD ID		07504
Ensembl ID		ENSG00000143870
Uniprot IDs		A0A384NPU5 Q15084
PDB IDs		1X5D 3VWW 3W8J 4EF0 4GWR
Enriched GO Terms of Interacting Partners?
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