PSMD12 and PSMD13 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- Hh ligand biogenesis disease
- T41 mutants of beta-catenin aren't phosphorylated
- Downstream signaling events of B Cell Receptor (BCR)
- Degradation of beta-catenin by the destruction complex
- Stabilization of p53
- S33 mutants of beta-catenin aren't phosphorylated
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- Removal of licensing factors from origins
- Switching of origins to a post-replicative state
- Mitotic G1-G1/S phases
- Regulation of mRNA stability by proteins that bind AU-rich elements
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- DNA Replication Pre-Initiation
- S45 mutants of beta-catenin aren't phosphorylated
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- Autodegradation of the E3 ubiquitin ligase COP1
- AMER1 mutants destabilize the destruction complex
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- PCP/CE pathway
- Adaptive Immune System
- CDK-mediated phosphorylation and removal of Cdc6
- Hedgehog ligand biogenesis
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Separation of Sister Chromatids
- HIV Infection
- Ubiquitin-dependent degradation of Cyclin D
- APC truncation mutants have impaired AXIN binding
- Assembly of the pre-replicative complex
- Autodegradation of Cdh1 by Cdh1:APC/C
- p53-Dependent G1 DNA Damage Response
- S37 mutants of beta-catenin aren't phosphorylated
- XAV939 inhibits tankyrase, stabilizing AXIN
- p53-Independent DNA Damage Response
- p53-Independent G1/S DNA damage checkpoint
- G1/S DNA Damage Checkpoints
- Vpu mediated degradation of CD4
- Synthesis of DNA
- M/G1 Transition
- Ubiquitin-dependent degradation of Cyclin D1
- TCF dependent signaling in response to WNT
- SCF-beta-TrCP mediated degradation of Emi1
- degradation of AXIN
- Signaling by Hedgehog
- Regulation of mitotic cell cycle
- Degradation of GLI1 by the proteasome
- degradation of DVL
- Cell Cycle Checkpoints
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Regulation of Apoptosis
- Degradation of GLI2 by the proteasome
- Signaling by the B Cell Receptor (BCR)
- Vif-mediated degradation of APOBEC3G
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- p53-Dependent G1/S DNA damage checkpoint
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Signaling by Wnt
- Cyclin E associated events during G1/S transition
- APC/C:Cdc20 mediated degradation of Securin
- AUF1 (hnRNP D0) destabilizes mRNA
- CDK-mediated phosphorylation and removal of Cdc6
- RNF mutants show enhanced WNT signaling and proliferation
- G1/S Transition
- truncations of AMER1 destabilize the destruction complex
- Processing-defective Hh variants abrogate ligand secretion
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- AXIN missense mutants destabilize the destruction complex
- S Phase
- APC/C-mediated degradation of cell cycle proteins
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic Metaphase and Anaphase
- Regulation of ornithine decarboxylase (ODC)
- Antigen processing: Ubiquitination & Proteasome degradation
- Orc1 removal from chromatin
- Mitotic Anaphase
- M Phase
- APC truncation mutants are not K63 polyubiquitinated
- Metabolism of amino acids and derivatives
- Hedgehog 'on' state
- Programmed Cell Death
- Class I MHC mediated antigen processing & presentation
- Regulation of DNA replication
- Cell Cycle, Mitotic
- beta-catenin independent WNT signaling
- Orc1 removal from chromatin
- Activation of NF-kappaB in B cells
- Asymmetric localization of PCP proteins
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Cross-presentation of soluble exogenous antigens (endosomes)
- Antigen processing-Cross presentation
- CDT1 association with the CDC6:ORC:origin complex
- ER-Phagosome pathway
|
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- Hh ligand biogenesis disease
- T41 mutants of beta-catenin aren't phosphorylated
- Downstream signaling events of B Cell Receptor (BCR)
- Degradation of beta-catenin by the destruction complex
- Stabilization of p53
- S33 mutants of beta-catenin aren't phosphorylated
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- Removal of licensing factors from origins
- Switching of origins to a post-replicative state
- Mitotic G1-G1/S phases
- Regulation of mRNA stability by proteins that bind AU-rich elements
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- DNA Replication Pre-Initiation
- S45 mutants of beta-catenin aren't phosphorylated
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- Autodegradation of the E3 ubiquitin ligase COP1
- AMER1 mutants destabilize the destruction complex
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- PCP/CE pathway
- Adaptive Immune System
- CDK-mediated phosphorylation and removal of Cdc6
- Hedgehog ligand biogenesis
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Separation of Sister Chromatids
- HIV Infection
- Ubiquitin-dependent degradation of Cyclin D
- APC truncation mutants have impaired AXIN binding
- Assembly of the pre-replicative complex
- Autodegradation of Cdh1 by Cdh1:APC/C
- p53-Dependent G1 DNA Damage Response
- S37 mutants of beta-catenin aren't phosphorylated
- XAV939 inhibits tankyrase, stabilizing AXIN
- p53-Independent DNA Damage Response
- p53-Independent G1/S DNA damage checkpoint
- G1/S DNA Damage Checkpoints
- Vpu mediated degradation of CD4
- Synthesis of DNA
- M/G1 Transition
- Ubiquitin-dependent degradation of Cyclin D1
- TCF dependent signaling in response to WNT
- SCF-beta-TrCP mediated degradation of Emi1
- degradation of AXIN
- Signaling by Hedgehog
- Regulation of mitotic cell cycle
- Degradation of GLI1 by the proteasome
- degradation of DVL
- Cell Cycle Checkpoints
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Regulation of Apoptosis
- Degradation of GLI2 by the proteasome
- Signaling by the B Cell Receptor (BCR)
- Vif-mediated degradation of APOBEC3G
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- p53-Dependent G1/S DNA damage checkpoint
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Signaling by Wnt
- Cyclin E associated events during G1/S transition
- APC/C:Cdc20 mediated degradation of Securin
- AUF1 (hnRNP D0) destabilizes mRNA
- CDK-mediated phosphorylation and removal of Cdc6
- RNF mutants show enhanced WNT signaling and proliferation
- G1/S Transition
- truncations of AMER1 destabilize the destruction complex
- Processing-defective Hh variants abrogate ligand secretion
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- AXIN missense mutants destabilize the destruction complex
- S Phase
- APC/C-mediated degradation of cell cycle proteins
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic Metaphase and Anaphase
- Regulation of ornithine decarboxylase (ODC)
- Antigen processing: Ubiquitination & Proteasome degradation
- Orc1 removal from chromatin
- Mitotic Anaphase
- M Phase
- APC truncation mutants are not K63 polyubiquitinated
- Metabolism of amino acids and derivatives
- Hedgehog 'on' state
- Programmed Cell Death
- Class I MHC mediated antigen processing & presentation
- Regulation of DNA replication
- Cell Cycle, Mitotic
- beta-catenin independent WNT signaling
- Orc1 removal from chromatin
- Activation of NF-kappaB in B cells
- Asymmetric localization of PCP proteins
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Cross-presentation of soluble exogenous antigens (endosomes)
- Antigen processing-Cross presentation
- CDT1 association with the CDC6:ORC:origin complex
- ER-Phagosome pathway
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PSME1 and PSME2 |
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- Hh ligand biogenesis disease
- T41 mutants of beta-catenin aren't phosphorylated
- Downstream signaling events of B Cell Receptor (BCR)
- Degradation of beta-catenin by the destruction complex
- Stabilization of p53
- S33 mutants of beta-catenin aren't phosphorylated
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- Removal of licensing factors from origins
- Switching of origins to a post-replicative state
- Mitotic G1-G1/S phases
- Regulation of mRNA stability by proteins that bind AU-rich elements
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- DNA Replication Pre-Initiation
- S45 mutants of beta-catenin aren't phosphorylated
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- Autodegradation of the E3 ubiquitin ligase COP1
- AMER1 mutants destabilize the destruction complex
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- PCP/CE pathway
- Adaptive Immune System
- CDK-mediated phosphorylation and removal of Cdc6
- Hedgehog ligand biogenesis
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Separation of Sister Chromatids
- HIV Infection
- Ubiquitin-dependent degradation of Cyclin D
- APC truncation mutants have impaired AXIN binding
- Assembly of the pre-replicative complex
- Autodegradation of Cdh1 by Cdh1:APC/C
- p53-Dependent G1 DNA Damage Response
- S37 mutants of beta-catenin aren't phosphorylated
- XAV939 inhibits tankyrase, stabilizing AXIN
- p53-Independent DNA Damage Response
- p53-Independent G1/S DNA damage checkpoint
- G1/S DNA Damage Checkpoints
- Vpu mediated degradation of CD4
- Synthesis of DNA
- M/G1 Transition
- Ubiquitin-dependent degradation of Cyclin D1
- TCF dependent signaling in response to WNT
- SCF-beta-TrCP mediated degradation of Emi1
- degradation of AXIN
- Signaling by Hedgehog
- Regulation of mitotic cell cycle
- Degradation of GLI1 by the proteasome
- degradation of DVL
- Cell Cycle Checkpoints
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Regulation of Apoptosis
- Degradation of GLI2 by the proteasome
- Signaling by the B Cell Receptor (BCR)
- Vif-mediated degradation of APOBEC3G
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- p53-Dependent G1/S DNA damage checkpoint
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Signaling by Wnt
- Cyclin E associated events during G1/S transition
- APC/C:Cdc20 mediated degradation of Securin
- AUF1 (hnRNP D0) destabilizes mRNA
- CDK-mediated phosphorylation and removal of Cdc6
- RNF mutants show enhanced WNT signaling and proliferation
- G1/S Transition
- truncations of AMER1 destabilize the destruction complex
- Processing-defective Hh variants abrogate ligand secretion
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- AXIN missense mutants destabilize the destruction complex
- S Phase
- APC/C-mediated degradation of cell cycle proteins
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic Metaphase and Anaphase
- Regulation of ornithine decarboxylase (ODC)
- Antigen processing: Ubiquitination & Proteasome degradation
- Orc1 removal from chromatin
- Mitotic Anaphase
- M Phase
- APC truncation mutants are not K63 polyubiquitinated
- Metabolism of amino acids and derivatives
- Hedgehog 'on' state
- Programmed Cell Death
- Class I MHC mediated antigen processing & presentation
- Regulation of DNA replication
- Cell Cycle, Mitotic
- beta-catenin independent WNT signaling
- Orc1 removal from chromatin
- Activation of NF-kappaB in B cells
- Asymmetric localization of PCP proteins
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Cross-presentation of soluble exogenous antigens (endosomes)
- Antigen processing-Cross presentation
- CDT1 association with the CDC6:ORC:origin complex
- ER-Phagosome pathway
|
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- Hh ligand biogenesis disease
- T41 mutants of beta-catenin aren't phosphorylated
- Downstream signaling events of B Cell Receptor (BCR)
- Degradation of beta-catenin by the destruction complex
- Stabilization of p53
- S33 mutants of beta-catenin aren't phosphorylated
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- Removal of licensing factors from origins
- Switching of origins to a post-replicative state
- Mitotic G1-G1/S phases
- Regulation of mRNA stability by proteins that bind AU-rich elements
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- DNA Replication Pre-Initiation
- S45 mutants of beta-catenin aren't phosphorylated
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- Autodegradation of the E3 ubiquitin ligase COP1
- AMER1 mutants destabilize the destruction complex
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- PCP/CE pathway
- Adaptive Immune System
- CDK-mediated phosphorylation and removal of Cdc6
- Hedgehog ligand biogenesis
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Separation of Sister Chromatids
- HIV Infection
- Ubiquitin-dependent degradation of Cyclin D
- APC truncation mutants have impaired AXIN binding
- Assembly of the pre-replicative complex
- Autodegradation of Cdh1 by Cdh1:APC/C
- p53-Dependent G1 DNA Damage Response
- S37 mutants of beta-catenin aren't phosphorylated
- XAV939 inhibits tankyrase, stabilizing AXIN
- p53-Independent DNA Damage Response
- p53-Independent G1/S DNA damage checkpoint
- G1/S DNA Damage Checkpoints
- Vpu mediated degradation of CD4
- Synthesis of DNA
- M/G1 Transition
- Ubiquitin-dependent degradation of Cyclin D1
- TCF dependent signaling in response to WNT
- SCF-beta-TrCP mediated degradation of Emi1
- degradation of AXIN
- Signaling by Hedgehog
- Regulation of mitotic cell cycle
- Degradation of GLI1 by the proteasome
- degradation of DVL
- Cell Cycle Checkpoints
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Regulation of Apoptosis
- Degradation of GLI2 by the proteasome
- Signaling by the B Cell Receptor (BCR)
- Vif-mediated degradation of APOBEC3G
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- p53-Dependent G1/S DNA damage checkpoint
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Signaling by Wnt
- Cyclin E associated events during G1/S transition
- APC/C:Cdc20 mediated degradation of Securin
- AUF1 (hnRNP D0) destabilizes mRNA
- CDK-mediated phosphorylation and removal of Cdc6
- RNF mutants show enhanced WNT signaling and proliferation
- G1/S Transition
- truncations of AMER1 destabilize the destruction complex
- Processing-defective Hh variants abrogate ligand secretion
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- AXIN missense mutants destabilize the destruction complex
- S Phase
- APC/C-mediated degradation of cell cycle proteins
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic Metaphase and Anaphase
- Regulation of ornithine decarboxylase (ODC)
- Antigen processing: Ubiquitination & Proteasome degradation
- Orc1 removal from chromatin
- Mitotic Anaphase
- M Phase
- APC truncation mutants are not K63 polyubiquitinated
- Metabolism of amino acids and derivatives
- Hedgehog 'on' state
- Programmed Cell Death
- Class I MHC mediated antigen processing & presentation
- Regulation of DNA replication
- Cell Cycle, Mitotic
- beta-catenin independent WNT signaling
- Orc1 removal from chromatin
- Activation of NF-kappaB in B cells
- Asymmetric localization of PCP proteins
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Cross-presentation of soluble exogenous antigens (endosomes)
- Antigen processing-Cross presentation
- CDT1 association with the CDC6:ORC:origin complex
- ER-Phagosome pathway
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RAN and RANBP1 |
RAN, member RAS oncogene family |
RAN binding protein 1 |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
|
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- HIV Infection
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
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RAN and RANBP2 |
RAN, member RAS oncogene family |
RAN binding protein 2 |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
|
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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RAN and RANGAP1 |
RAN, member RAS oncogene family |
Ran GTPase activating protein 1 |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
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- Mitotic Prometaphase
- Separation of Sister Chromatids
- HIV Infection
- Host Interactions of HIV factors
- Rev-mediated nuclear export of HIV RNA
- Mitotic Anaphase
- Interactions of Rev with host cellular proteins
- M Phase
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- Resolution of Sister Chromatid Cohesion
- Mitotic Metaphase and Anaphase
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RAN and XPO1 |
RAN, member RAS oncogene family |
exportin 1 |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
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- Loss of Function of TGFBR2 in Cancer
- Downregulation of TGF-beta receptor signaling
- SMAD2/3 MH2 Domain Mutants in Cancer
- Signaling by Wnt
- TGF-beta receptor signaling activates SMADs
- Influenza Life Cycle
- Export of Viral Ribonucleoproteins from Nucleus
- RNF mutants show enhanced WNT signaling and proliferation
- Regulation of mRNA stability by proteins that bind AU-rich elements
- TGFBR2 MSI Frameshift Mutants in Cancer
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- Host Interactions of HIV factors
- Loss of Function of SMAD4 in Cancer
- TGFBR1 KD Mutants in Cancer
- Influenza Infection
- Late Phase of HIV Life Cycle
- Resolution of Sister Chromatid Cohesion
- Mitotic G2-G2/M phases
- Mitotic Metaphase and Anaphase
- Mitotic Prometaphase
- Separation of Sister Chromatids
- HIV Infection
- Rev-mediated nuclear export of HIV RNA
- G2/M Transition
- Mitotic Anaphase
- TGFBR1 LBD Mutants in Cancer
- HuR stabilizes mRNA
- deactivation of the beta-catenin transactivating complex
- M Phase
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- Cyclin A/B1 associated events during G2/M transition
- XAV939 inhibits tankyrase, stabilizing AXIN
- NEP/NS2 Interacts with the Cellular Export Machinery
- Loss of Function of SMAD2/3 in Cancer
- TGFBR2 Kinase Domain Mutants in Cancer
- Interactions of Rev with host cellular proteins
- Cell Cycle, Mitotic
- Loss of Function of TGFBR1 in Cancer
- Signaling by TGF-beta Receptor Complex
- Signaling by TGF-beta Receptor Complex in Cancer
- TCF dependent signaling in response to WNT
- Signaling by WNT in cancer
- SMAD4 MH2 Domain Mutants in Cancer
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RAN and NUP50 |
RAN, member RAS oncogene family |
nucleoporin 50kDa |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
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- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Nuclear Pore Complex (NPC) Disassembly
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
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RAN and SSRP1 |
RAN, member RAS oncogene family |
structure specific recognition protein 1 |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
|
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription
- HIV Infection
- Tat-mediated elongation of the HIV-1 transcript
- Tat-mediated HIV elongation arrest and recovery
- RNA Polymerase II Pre-transcription Events
- Late Phase of HIV Life Cycle
- Pausing and recovery of Tat-mediated HIV elongation
- Formation of RNA Pol II elongation complex
- HIV elongation arrest and recovery
- HIV Life Cycle
- Pausing and recovery of HIV elongation
- Formation of HIV elongation complex in the absence of HIV Tat
- HIV Transcription Elongation
- Transcription of the HIV genome
- RNA Polymerase II Transcription Elongation
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RAN and NUP153 |
RAN, member RAS oncogene family |
nucleoporin 153kDa |
- Transcriptional regulation by small RNAs
- Metabolism of lipids and lipoproteins
- Nuclear import of Rev protein
- HIV Infection
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- MicroRNA (miRNA) biogenesis
- Influenza Infection
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
- Influenza Life Cycle
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- Export of Viral Ribonucleoproteins from Nucleus
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
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- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Nuclear Pore Complex (NPC) Disassembly
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
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RANBP1 and XPO1 |
RAN binding protein 1 |
exportin 1 |
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- HIV Infection
- Rev-mediated nuclear export of HIV RNA
- Host Interactions of HIV factors
- Interactions of Rev with host cellular proteins
- Late Phase of HIV Life Cycle
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- Loss of Function of TGFBR2 in Cancer
- Downregulation of TGF-beta receptor signaling
- SMAD2/3 MH2 Domain Mutants in Cancer
- Signaling by Wnt
- TGF-beta receptor signaling activates SMADs
- Influenza Life Cycle
- Export of Viral Ribonucleoproteins from Nucleus
- RNF mutants show enhanced WNT signaling and proliferation
- Regulation of mRNA stability by proteins that bind AU-rich elements
- TGFBR2 MSI Frameshift Mutants in Cancer
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- Host Interactions of HIV factors
- Loss of Function of SMAD4 in Cancer
- TGFBR1 KD Mutants in Cancer
- Influenza Infection
- Late Phase of HIV Life Cycle
- Resolution of Sister Chromatid Cohesion
- Mitotic G2-G2/M phases
- Mitotic Metaphase and Anaphase
- Mitotic Prometaphase
- Separation of Sister Chromatids
- HIV Infection
- Rev-mediated nuclear export of HIV RNA
- G2/M Transition
- Mitotic Anaphase
- TGFBR1 LBD Mutants in Cancer
- HuR stabilizes mRNA
- deactivation of the beta-catenin transactivating complex
- M Phase
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- Cyclin A/B1 associated events during G2/M transition
- XAV939 inhibits tankyrase, stabilizing AXIN
- NEP/NS2 Interacts with the Cellular Export Machinery
- Loss of Function of SMAD2/3 in Cancer
- TGFBR2 Kinase Domain Mutants in Cancer
- Interactions of Rev with host cellular proteins
- Cell Cycle, Mitotic
- Loss of Function of TGFBR1 in Cancer
- Signaling by TGF-beta Receptor Complex
- Signaling by TGF-beta Receptor Complex in Cancer
- TCF dependent signaling in response to WNT
- Signaling by WNT in cancer
- SMAD4 MH2 Domain Mutants in Cancer
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RANBP2 and RANGAP1 |
RAN binding protein 2 |
Ran GTPase activating protein 1 |
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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- Mitotic Prometaphase
- Separation of Sister Chromatids
- HIV Infection
- Host Interactions of HIV factors
- Rev-mediated nuclear export of HIV RNA
- Mitotic Anaphase
- Interactions of Rev with host cellular proteins
- M Phase
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- Resolution of Sister Chromatid Cohesion
- Mitotic Metaphase and Anaphase
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RANBP2 and TAF1 |
RAN binding protein 2 |
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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- RNA Polymerase II Promoter Escape
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
- RNA Polymerase II Transcription
- HIV Infection
- RNA Polymerase II Pre-transcription Events
- Late Phase of HIV Life Cycle
- HIV Life Cycle
- HIV Transcription Initiation
- RNA Polymerase II Transcription Initiation And Promoter Clearance
- RNA Polymerase II HIV Promoter Escape
- RNA Polymerase II Transcription Initiation
- Transcription of the HIV genome
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RANBP2 and XPO1 |
RAN binding protein 2 |
exportin 1 |
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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- Loss of Function of TGFBR2 in Cancer
- Downregulation of TGF-beta receptor signaling
- SMAD2/3 MH2 Domain Mutants in Cancer
- Signaling by Wnt
- TGF-beta receptor signaling activates SMADs
- Influenza Life Cycle
- Export of Viral Ribonucleoproteins from Nucleus
- RNF mutants show enhanced WNT signaling and proliferation
- Regulation of mRNA stability by proteins that bind AU-rich elements
- TGFBR2 MSI Frameshift Mutants in Cancer
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- Host Interactions of HIV factors
- Loss of Function of SMAD4 in Cancer
- TGFBR1 KD Mutants in Cancer
- Influenza Infection
- Late Phase of HIV Life Cycle
- Resolution of Sister Chromatid Cohesion
- Mitotic G2-G2/M phases
- Mitotic Metaphase and Anaphase
- Mitotic Prometaphase
- Separation of Sister Chromatids
- HIV Infection
- Rev-mediated nuclear export of HIV RNA
- G2/M Transition
- Mitotic Anaphase
- TGFBR1 LBD Mutants in Cancer
- HuR stabilizes mRNA
- deactivation of the beta-catenin transactivating complex
- M Phase
- HIV Life Cycle
- Rev-mediated nuclear export of HIV RNA
- Cyclin A/B1 associated events during G2/M transition
- XAV939 inhibits tankyrase, stabilizing AXIN
- NEP/NS2 Interacts with the Cellular Export Machinery
- Loss of Function of SMAD2/3 in Cancer
- TGFBR2 Kinase Domain Mutants in Cancer
- Interactions of Rev with host cellular proteins
- Cell Cycle, Mitotic
- Loss of Function of TGFBR1 in Cancer
- Signaling by TGF-beta Receptor Complex
- Signaling by TGF-beta Receptor Complex in Cancer
- TCF dependent signaling in response to WNT
- Signaling by WNT in cancer
- SMAD4 MH2 Domain Mutants in Cancer
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RANBP2 and NUP62 |
RAN binding protein 2 |
nucleoporin 62kDa |
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Nuclear Pore Complex (NPC) Disassembly
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
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SKP1 and BTRC |
S-phase kinase-associated protein 1 |
beta-transducin repeat containing E3 ubiquitin protein ligase |
- Signaling by the B Cell Receptor (BCR)
- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- T41 mutants of beta-catenin aren't phosphorylated
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Cyclin E associated events during G1/S transition
- Signaling by Wnt
- Regulation of PLK1 Activity at G2/M Transition
- Downstream signaling events of B Cell Receptor (BCR)
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- Degradation of beta-catenin by the destruction complex
- G1/S Transition
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- S33 mutants of beta-catenin aren't phosphorylated
- Signaling by NOTCH1 in Cancer
- Prolactin receptor signaling
- Mitotic G1-G1/S phases
- truncations of AMER1 destabilize the destruction complex
- Signaling by NOTCH
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- AXIN missense mutants destabilize the destruction complex
- S45 mutants of beta-catenin aren't phosphorylated
- Regulation of APC/C activators between G1/S and early anaphase
- S Phase
- Signaling by ERBB4
- APC/C-mediated degradation of cell cycle proteins
- Signaling by Interleukins
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- AMER1 mutants destabilize the destruction complex
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Interleukin-1 signaling
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic G2-G2/M phases
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Adaptive Immune System
- Antigen processing: Ubiquitination & Proteasome degradation
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- HIV Infection
- APC truncation mutants have impaired AXIN binding
- G2/M Transition
- APC truncation mutants are not K63 polyubiquitinated
- S37 mutants of beta-catenin aren't phosphorylated
- Signaling by NOTCH1
- Class I MHC mediated antigen processing & presentation
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
- FBXW7 Mutants and NOTCH1 in Cancer
- Vpu mediated degradation of CD4
- G1 Phase
- Cytokine Signaling in Immune system
- Cell Cycle, Mitotic
- NOTCH1 Intracellular Domain Regulates Transcription
- Cyclin D associated events in G1
- Nuclear signaling by ERBB4
- Activation of NF-kappaB in B cells
- SCF-beta-TrCP mediated degradation of Emi1
- Regulation of mitotic cell cycle
- Signaling by Hedgehog
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Degradation of GLI1 by the proteasome
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Degradation of GLI2 by the proteasome
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- Signaling by the B Cell Receptor (BCR)
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- T41 mutants of beta-catenin aren't phosphorylated
- TCF7L2 mutants don't bind CTBP
- truncated APC mutants destabilize the destruction complex
- Signaling by Wnt
- Regulation of PLK1 Activity at G2/M Transition
- Downstream signaling events of B Cell Receptor (BCR)
- Degradation of beta-catenin by the destruction complex
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- S33 mutants of beta-catenin aren't phosphorylated
- RNF mutants show enhanced WNT signaling and proliferation
- Prolactin receptor signaling
- truncations of AMER1 destabilize the destruction complex
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- Host Interactions of HIV factors
- AXIN missense mutants destabilize the destruction complex
- S45 mutants of beta-catenin aren't phosphorylated
- Regulation of APC/C activators between G1/S and early anaphase
- Signaling by ERBB4
- APC/C-mediated degradation of cell cycle proteins
- Signaling by Interleukins
- deletions in the AMER1 gene destabilize the destruction complex
- AMER1 mutants destabilize the destruction complex
- Interleukin-1 signaling
- Mitotic G2-G2/M phases
- Adaptive Immune System
- Antigen processing: Ubiquitination & Proteasome degradation
- APC truncation mutants have impaired AXIN binding
- HIV Infection
- G2/M Transition
- deactivation of the beta-catenin transactivating complex
- APC truncation mutants are not K63 polyubiquitinated
- S37 mutants of beta-catenin aren't phosphorylated
- XAV939 inhibits tankyrase, stabilizing AXIN
- Class I MHC mediated antigen processing & presentation
- Vpu mediated degradation of CD4
- Cytokine Signaling in Immune system
- Cell Cycle, Mitotic
- Nuclear signaling by ERBB4
- TCF dependent signaling in response to WNT
- Activation of NF-kappaB in B cells
- SCF-beta-TrCP mediated degradation of Emi1
- Regulation of mitotic cell cycle
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Signaling by Hedgehog
- Degradation of GLI1 by the proteasome
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Degradation of GLI2 by the proteasome
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SKP1 and RBX1 |
S-phase kinase-associated protein 1 |
ring-box 1, E3 ubiquitin protein ligase |
- Signaling by the B Cell Receptor (BCR)
- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- T41 mutants of beta-catenin aren't phosphorylated
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Cyclin E associated events during G1/S transition
- Signaling by Wnt
- Regulation of PLK1 Activity at G2/M Transition
- Downstream signaling events of B Cell Receptor (BCR)
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- Degradation of beta-catenin by the destruction complex
- G1/S Transition
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- S33 mutants of beta-catenin aren't phosphorylated
- Signaling by NOTCH1 in Cancer
- Prolactin receptor signaling
- Mitotic G1-G1/S phases
- truncations of AMER1 destabilize the destruction complex
- Signaling by NOTCH
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- AXIN missense mutants destabilize the destruction complex
- S45 mutants of beta-catenin aren't phosphorylated
- Regulation of APC/C activators between G1/S and early anaphase
- S Phase
- Signaling by ERBB4
- APC/C-mediated degradation of cell cycle proteins
- Signaling by Interleukins
- SCF(Skp2)-mediated degradation of p27/p21
- deletions in the AMER1 gene destabilize the destruction complex
- AMER1 mutants destabilize the destruction complex
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Interleukin-1 signaling
- Cyclin A:Cdk2-associated events at S phase entry
- SCF(Skp2)-mediated degradation of p27/p21
- Mitotic G2-G2/M phases
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Adaptive Immune System
- Antigen processing: Ubiquitination & Proteasome degradation
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- HIV Infection
- APC truncation mutants have impaired AXIN binding
- G2/M Transition
- APC truncation mutants are not K63 polyubiquitinated
- S37 mutants of beta-catenin aren't phosphorylated
- Signaling by NOTCH1
- Class I MHC mediated antigen processing & presentation
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
- FBXW7 Mutants and NOTCH1 in Cancer
- Vpu mediated degradation of CD4
- G1 Phase
- Cytokine Signaling in Immune system
- Cell Cycle, Mitotic
- NOTCH1 Intracellular Domain Regulates Transcription
- Cyclin D associated events in G1
- Nuclear signaling by ERBB4
- Activation of NF-kappaB in B cells
- SCF-beta-TrCP mediated degradation of Emi1
- Regulation of mitotic cell cycle
- Signaling by Hedgehog
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Degradation of GLI1 by the proteasome
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Degradation of GLI2 by the proteasome
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- Vif-mediated degradation of APOBEC3G
- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Hedgehog 'off' state
- misspliced GSK3beta mutants stabilize beta-catenin
- T41 mutants of beta-catenin aren't phosphorylated
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Signaling by Wnt
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- Degradation of beta-catenin by the destruction complex
- RNF mutants show enhanced WNT signaling and proliferation
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- S33 mutants of beta-catenin aren't phosphorylated
- Signaling by NOTCH1 in Cancer
- Prolactin receptor signaling
- truncations of AMER1 destabilize the destruction complex
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- Signaling by NOTCH
- Host Interactions of HIV factors
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- AXIN missense mutants destabilize the destruction complex
- S45 mutants of beta-catenin aren't phosphorylated
- Signaling by ERBB4
- Signaling by Interleukins
- deletions in the AMER1 gene destabilize the destruction complex
- AMER1 mutants destabilize the destruction complex
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Interleukin-1 signaling
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Adaptive Immune System
- Cellular response to hypoxia
- Antigen processing: Ubiquitination & Proteasome degradation
- Regulation of Hypoxia-inducible Factor (HIF) by oxygen
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- HIV Infection
- APC truncation mutants have impaired AXIN binding
- APC truncation mutants are not K63 polyubiquitinated
- S37 mutants of beta-catenin aren't phosphorylated
- Hedgehog 'on' state
- Signaling by NOTCH1
- XAV939 inhibits tankyrase, stabilizing AXIN
- Class I MHC mediated antigen processing & presentation
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
- FBXW7 Mutants and NOTCH1 in Cancer
- Cytokine Signaling in Immune system
- Nuclear signaling by ERBB4
- NOTCH1 Intracellular Domain Regulates Transcription
- TCF dependent signaling in response to WNT
- Signaling by Hedgehog
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- Degradation of GLI1 by the proteasome
- degradation of DVL
- Signaling by WNT in cancer
- GLI3 is processed to GLI3R by the proteasome
- Degradation of GLI2 by the proteasome
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SSRP1 and HIST1H4A |
structure specific recognition protein 1 |
histone cluster 1, H4a |
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription
- HIV Infection
- Tat-mediated elongation of the HIV-1 transcript
- Tat-mediated HIV elongation arrest and recovery
- RNA Polymerase II Pre-transcription Events
- Late Phase of HIV Life Cycle
- Pausing and recovery of Tat-mediated HIV elongation
- Formation of RNA Pol II elongation complex
- HIV elongation arrest and recovery
- HIV Life Cycle
- Pausing and recovery of HIV elongation
- Formation of HIV elongation complex in the absence of HIV Tat
- HIV Transcription Elongation
- Transcription of the HIV genome
- RNA Polymerase II Transcription Elongation
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- RNA Polymerase I Chain Elongation
- RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
- Mitotic Prophase
- PKMTs methylate histone lysines
- Regulatory RNA pathways
- RNA Polymerase I Promoter Clearance
- Deposition of new CENPA-containing nucleosomes at the centromere
- HDMs demethylate histones
- Cellular Senescence
- Signaling by Wnt
- HATs acetylate histones
- M Phase
- Amyloids
- NoRC negatively regulates rRNA expression
- Packaging Of Telomere Ends
- Telomere Maintenance
- Nucleosome assembly
- RNF mutants show enhanced WNT signaling and proliferation
- XAV939 inhibits tankyrase, stabilizing AXIN
- DNA methylation
- Transcriptional regulation by small RNAs
- Meiotic recombination
- DNA Damage/Telomere Stress Induced Senescence
- Chromosome Maintenance
- HDACs deacetylate histones
- Chromatin organization
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- RNA Polymerase I Transcription
- formation of the beta-catenin:TCF transactivating complex
- Meiotic synapsis
- Epigenetic regulation of gene expression
- Senescence-Associated Secretory Phenotype (SASP)
- Negative epigenetic regulation of rRNA expression
- PRC2 methylates histones and DNA
- Cell Cycle, Mitotic
- RMTs methylate histone arginines
- Chromatin modifying enzymes
- Oxidative Stress Induced Senescence
- TCF dependent signaling in response to WNT
- RNA Polymerase I Promoter Opening
- SIRT1 negatively regulates rRNA Expression
- Signaling by WNT in cancer
- Condensation of Prophase Chromosomes
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NUP133 and NUP107 |
nucleoporin 133kDa |
nucleoporin 107kDa |
- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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- Mitotic Prometaphase
- Separation of Sister Chromatids
- Mitotic Prophase
- HIV Infection
- Nuclear import of Rev protein
- Regulatory RNA pathways
- Rev-mediated nuclear export of HIV RNA
- Nuclear Envelope Breakdown
- Mitotic Anaphase
- SLC-mediated transmembrane transport
- M Phase
- Influenza Life Cycle
- HIV Life Cycle
- Influenza Viral RNA Transcription and Replication
- Rev-mediated nuclear export of HIV RNA
- Myoclonic epilepsy of Lafora
- Glycogen storage diseases
- Transcriptional regulation by small RNAs
- Vpr-mediated nuclear import of PICs
- ISG15 antiviral mechanism
- Interferon Signaling
- Host Interactions of HIV factors
- Regulation of Glucokinase by Glucokinase Regulatory Protein
- Nuclear Pore Complex (NPC) Disassembly
- Cytokine Signaling in Immune system
- Interactions of Vpr with host cellular proteins
- Interactions of Rev with host cellular proteins
- Influenza Infection
- Hexose transport
- Cell Cycle, Mitotic
- Late Phase of HIV Life Cycle
- Antiviral mechanism by IFN-stimulated genes
- Resolution of Sister Chromatid Cohesion
- Viral Messenger RNA Synthesis
- Metabolism of carbohydrates
- Glucose transport
- Mitotic Metaphase and Anaphase
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SUPT4H1 and XRCC5 |
suppressor of Ty 4 homolog 1 (S. cerevisiae) |
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription
- Abortive elongation of HIV-1 transcript in the absence of Tat
- HIV Infection
- Formation of the Early Elongation Complex
- Tat-mediated elongation of the HIV-1 transcript
- Tat-mediated HIV elongation arrest and recovery
- RNA Polymerase II Pre-transcription Events
- Late Phase of HIV Life Cycle
- Pausing and recovery of Tat-mediated HIV elongation
- Formation of RNA Pol II elongation complex
- HIV elongation arrest and recovery
- HIV Life Cycle
- Pausing and recovery of HIV elongation
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- HIV Transcription Elongation
- Transcription of the HIV genome
- RNA Polymerase II Transcription Elongation
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- Cytosolic sensors of pathogen-associated DNA
- HIV Infection
- Processing of DNA ends prior to end rejoining
- Integration of provirus
- Early Phase of HIV Life Cycle
- HIV Life Cycle
- Nonhomologous End-joining (NHEJ)
- STING mediated induction of host immune responses
- Double-Strand Break Repair
- IRF3-mediated induction of type I IFN
- 2-LTR circle formation
- Innate Immune System
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SUPT4H1 and HTATSF1 |
suppressor of Ty 4 homolog 1 (S. cerevisiae) |
HIV-1 Tat specific factor 1 |
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription
- Abortive elongation of HIV-1 transcript in the absence of Tat
- HIV Infection
- Formation of the Early Elongation Complex
- Tat-mediated elongation of the HIV-1 transcript
- Tat-mediated HIV elongation arrest and recovery
- RNA Polymerase II Pre-transcription Events
- Late Phase of HIV Life Cycle
- Pausing and recovery of Tat-mediated HIV elongation
- Formation of RNA Pol II elongation complex
- HIV elongation arrest and recovery
- HIV Life Cycle
- Pausing and recovery of HIV elongation
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- HIV Transcription Elongation
- Transcription of the HIV genome
- RNA Polymerase II Transcription Elongation
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