DAZAP2 and COL4A2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DAZAP2	COL4A2
Gene Name		DAZ associated protein 2	collagen, type IV, alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Collagen Type IV Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding WW Domain Binding	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process		Angiogenesis Transcription, DNA-templated Receptor-mediated Endocytosis Axon Guidance Negative Regulation Of Angiogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth Scavenging by Class A Receptors
Drugs
Diseases
GWAS			Coronary artery calcification ( 22144573) Coronary heart disease ( 21378990)
Protein-Protein Interactions		86 interactors: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FAM46B FAM46C FBN3 GPSM1 HGS HIP1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MED31 NDUFA5 NEDD4 NEDD4L NOC4L OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPT2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581	23 interactors: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FAM46A FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TGFBI TK1
Entrez ID		9802	1284
HPRD ID		08463	00355
Ensembl ID		ENSG00000183283	ENSG00000134871
Uniprot IDs		E9PB45 Q15038	P08572
PDB IDs			1LI1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Protein Processing Regulation Of ERBB Signaling Pathway Protein Ubiquitination Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Signaling Intracellular Transport Of Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Metabolic Process RNA Biosynthetic Process Endosomal Transport Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type I Interferon Production Transforming Growth Factor Beta Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress	Extracellular Matrix Organization Extracellular Structure Organization Tissue Development Chemotaxis Anatomical Structure Development System Development Nervous System Development Axon Guidance Cell Morphogenesis Involved In Differentiation Hemostasis Generation Of Neurons Developmental Process Multicellular Organismal Development Neurogenesis Cell Differentiation Locomotion Extracellular Matrix Disassembly Axonogenesis Response To External Stimulus Axon Development Regulation Of Body Fluid Levels Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To Wounding Blood Coagulation Endodermal Cell Differentiation Acute-phase Response Platelet Activation Neuron Projection Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Projection Morphogenesis Cell Development Peptide Cross-linking Reproductive Process Cell Part Morphogenesis Seminal Vesicle Epithelium Development Fetal Process Involved In Parturition Dendrite Regeneration Mating Neuromuscular Junction Development Leukocyte Migration Regulation Of Pathway-restricted SMAD Protein Phosphorylation Endoderm Formation Neuron Development Collagen Catabolic Process Regulation Of Binding Behavior
Tagcloud ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Difference) ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Intersection) ?