SNCAIP and C11orf58

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SNCAIP	C11orf58
Description		synuclein alpha interacting protein	chromosome 11 open reading frame 58
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Synaptic Vesicle Cytoplasmic Ribonucleoprotein Granule Presynaptic Membrane Neuronal Cell Body	Cellular_component
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Molecular_function
	Biological Process	Cell Death Dopamine Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Inclusion Body Assembly	Biological_process
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes ( 31537649) Delirium ( 29631748) Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mood disorder and prion disease ( 25897833) Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50) ( 27047539)	Chronotype ( 30696823) Coronary artery disease ( 33020668) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 28869591 30598549) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Lumbar spine bone mineral density ( 29499414) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		19 interacting genes: AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PIN1 PINK1 PPHLN1 PRKN PTN RNF19A SEPTIN4 SH2D3C SIAH1 SIAH2 SNCA TLE5 UBB	17 interacting genes: A2M CEBPA CEP126 EEF1G FBN3 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48
Entrez ID		9627	10944
HPRD ID		04804	18069
Ensembl ID		ENSG00000064692	ENSG00000110696
Uniprot IDs		B7Z616 B7Z995 Q6L981 Q6L983 Q9Y6H5	O00193
PDB IDs		2KES
Enriched GO Terms of Interacting Partners?		Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Lewy Body Amyloid Fibril Formation Ubiquitin Conjugating Enzyme Binding Regulation Of Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Apoptotic Signaling Pathway Regulation Of Post-translational Protein Modification Positive Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Dopamine Transport Proteolysis Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Dopamine Secretion Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Protein Stability Protein Ubiquitination Mitochondrial Outer Membrane Axon Regulation Of Protein Modification Process Mitochondrion To Lysosome Vesicle-mediated Transport Cellular Response To Hydrogen Sulfide Monoamine Transport Protein Modification By Small Protein Conjugation Regulation Of Canonical Wnt Signaling Pathway Regulation Of Neuron Apoptotic Process Response To Hydrogen Sulfide Regulation Of Apoptotic Process Proteasomal Protein Catabolic Process Regulation Of Programmed Cell Death Regulation Of Catecholamine Secretion Catabolic Process Negative Regulation Of Mitochondrial Fission Regulation Of Synaptic Vesicle Transport Regulation Of Protein Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Tau Protein Binding Positive Regulation Of Protein Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Post-translational Protein Modification Regulation Of Wnt Signaling Pathway Protein Modification Process Cytosol Negative Regulation Of Wnt Signaling Pathway See more
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?