RPS10 and TCF25

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPS10	TCF25
Gene Name		ribosomal protein S10	transcription factor 25 (basic helix-loop-helix)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Protein Binding Poly(A) RNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heart Development
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP DMPK DNMT3B DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6	8 interactors: APPBP2 CCDC155 DERL1 GPRASP2 MAGEA11 NEK2 RPS10 SAT1
Entrez ID		6204	22980
HPRD ID		04697	13830
Ensembl ID		ENSG00000124614	ENSG00000141002
Uniprot IDs		P46783	Q9BQ70
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Chromosome Organization Organelle Organization Gene Expression Regulation Of Vesicle-mediated Transport Positive Regulation Of Organelle Organization Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Protein Modification Process Genetic Imprinting Regulation Of Cell Differentiation Transcription, DNA-templated Positive Regulation Of Histone Methylation RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Catalytic Activity RNA Biosynthetic Process Positive Regulation Of Cell Cycle Process DNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Axon Cargo Transport Regulation Of Cellular Process Regulation Of Histone Methylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Regulation Of Cellular Component Organization Regulation Of Neurogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Platelet Degranulation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Histone Modification	Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation Of Centriole-centriole Cohesion Catabolic Process Spermidine Acetylation Establishment Of Localization In Cell Regulation Of Centriole-centriole Cohesion Putrescine Catabolic Process Cellular Macromolecule Catabolic Process Viral Life Cycle Intracellular Protein Transport Meiotic Cell Cycle Regulation Of Mitotic Centrosome Separation Oxalate Transport Intracellular Transport Of Viral Protein In Host Cell Retrograde Protein Transport, ER To Cytosol Chromosome Segregation Cellular Localization Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Neurotransmitter Uptake Cellular Protein Localization Protein Transport Centrosome Separation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Establishment Of Protein Localization Polyamine Biosynthetic Process Intracellular Transport Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Amine Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Modification-dependent Protein Catabolic Process Intracellular Transport Of Virus Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Polyamine Metabolic Process Cellular Protein Catabolic Process Protein Localization Protein Catabolic Process Sulfate Transmembrane Transport ER-associated Ubiquitin-dependent Protein Catabolic Process Establishment Of Chromosome Localization Sulfate Transport Mitotic Spindle Organization Negative Regulation Of DNA Binding Regulation Of Centrosome Cycle Neutral Amino Acid Transport
Tagcloud ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Difference) ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Intersection) ?