DNTT and ABTB2

Number of citations of the paper that reports this interaction (PubMedID 18429817)
0

Data Source:
HPRD (in vitro, in vivo)

		DNTT	ABTB2
Description		DNA nucleotidylexotransferase	ankyrin repeat and BTB domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity DNA Polymerase Activity Metal Ion Binding	Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process	Cellular Response To Toxic Substance
Pathways
Drugs		2',3'-Dideoxyadenosine triphosphate
Diseases
GWAS			Pre-treatment viral load in HIV-1 infection ( 31219150) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		9 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 XRCC6	3 interacting genes: CUL3 DNTT EEF1A1
Entrez ID		1791	25841
HPRD ID		08925	10624
Ensembl ID		ENSG00000107447	ENSG00000166016
Uniprot IDs		P04053	Q8N961
PDB IDs		2COE 5W4E
Enriched GO Terms of Interacting Partners?		Damaged DNA Binding DNA End Binding DNA Metabolic Process Telomere Maintenance Chromosome Organization Double-strand Break Repair Via Nonhomologous End Joining Ku70:Ku80 Complex Chromosome PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Beta-catenin-TCF7L2 Complex Negative Regulation Of Skeletal Muscle Tissue Growth See more	DNA Nucleotidylexotransferase Activity Macromolecule Biosynthetic Process Eukaryotic Translation Elongation Factor 1 Complex Regulation Protein Catabolic Process At Postsynapse Trophectodermal Cellular Morphogenesis POZ Domain Binding Liver Morphogenesis DNA Polymerase Activity DNA-directed DNA Polymerase Activity Kinase Activator Activity Host-mediated Perturbation Of Viral Genome Replication Cytoplasmic Side Of Lysosomal Membrane Host-mediated Activation Of Viral Genome Replication Translation Elongation Factor Activity Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Rho Protein Signal Transduction Renal Sodium Ion Transport Positive Regulation Of Mitotic Sister Chromatid Separation Embryonic Cleavage Notch Binding Ubiquitin Ligase Complex Scaffold Activity Cullin-RING Ubiquitin Ligase Complex Polar Microtubule Contractile Actin Filament Bundle Assembly Anaphase-promoting Complex-dependent Catabolic Process Fibroblast Apoptotic Process Stress Fiber Assembly Positive Regulation Of Mitotic Metaphase/anaphase Transition COPII Vesicle Coating RNA Polymerase II Transcription Initiation Surveillance Renal Sodium Ion Absorption Nuclear Protein Quality Control By The Ubiquitin-proteasome System Stem Cell Division DNA Modification Gland Morphogenesis See more
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