CEP57

Gene Name		centrosomal protein 57kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding
	Biological Process	Protein Import Into Nucleus, Translocation G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Microtubule Anchoring Protein Homooligomerization
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-protein Interactions		15 interactors: APP CEP63 CTAGE5 FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MYC RALBP1 TFIP11 UIMC1
Entrez ID		9702
HPRD ID		16261
Ensembl ID		ENSG00000166037
Uniprot IDs		F5GYW0 Q86XR8
PDB IDs		4L0R
Enriched GO Terms of Interacting Partners?		Response To Radiation Positive Regulation Of Catalytic Activity Tissue Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Spliceosomal Complex Disassembly Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Proliferation Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Response To DNA Damage Stimulus Ureteric Bud Morphogenesis Nephron Morphogenesis Developmental Process Renal Tubule Morphogenesis Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Skeletal Muscle Satellite Cell Activation Fibroblast Apoptotic Process Regulation Of Catalytic Activity Renal Tubule Development Cellular Metal Ion Homeostasis Positive Regulation Of Metabolic Process Kidney Morphogenesis Histone H2A K63-linked Deubiquitination Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Collateral Sprouting In Absence Of Injury Cellular Cation Homeostasis Cellular Ion Homeostasis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Metal Ion Homeostasis Positive Regulation Of Hydrolase Activity Cell Recognition Regulation Of Response To DNA Damage Stimulus Mesonephros Development Anatomical Structure Development Collateral Sprouting Axon Midline Choice Point Recognition Epithelium Development Regulation Of Striated Muscle Tissue Development Response To Abiotic Stimulus Notch Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Nephron Development Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Cellular Chemical Homeostasis Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis
Tagcloud ?		accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue