DSEL

Gene Name		dermatan sulfate epimerase-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Sulfotransferase Activity Isomerase Activity
	Biological Process	Carbohydrate Metabolic Process Pathogenesis Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Dermatan Sulfate Biosynthetic Process Small Molecule Metabolic Process
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Glycosaminoglycan metabolism Defective SLC26A2 causes chondrodysplasias Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases Defective CHST6 causes MCDC1 MPS IIID - Sanfilippo syndrome D MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Dermatan sulfate biosynthesis Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 20125088)
Protein-protein Interactions		1 interactors: SPP1
Entrez ID		92126
HPRD ID		10720
Ensembl ID		ENSG00000171451
Uniprot IDs		Q8IZU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Positive Regulation Of Bone Resorption Regulation Of Axon Regeneration Positive Regulation Of Tissue Remodeling Response To Vitamin D Decidualization Regulation Of Bone Resorption Maternal Placenta Development Regulation Of Bone Remodeling Neutrophil Chemotaxis Neutrophil Migration Granulocyte Chemotaxis Negative Regulation Of Axonogenesis Regulation Of Tissue Remodeling Biomineral Tissue Development Embryo Implantation Maternal Process Involved In Female Pregnancy Negative Regulation Of Developmental Growth Extracellular Matrix Disassembly Negative Regulation Of Cell Morphogenesis Involved In Differentiation Leukocyte Chemotaxis Response To Vitamin Negative Regulation Of Neuron Projection Development Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell Size Osteoblast Differentiation Negative Regulation Of Cell Projection Organization Negative Regulation Of Cell Growth Regulation Of Axonogenesis Cell Chemotaxis Negative Regulation Of Neuron Differentiation Placenta Development Regulation Of Cell-substrate Adhesion Response To Nutrient Leukocyte Migration Female Pregnancy Negative Regulation Of Growth Ossification Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Regulation Of Cellular Component Size Negative Regulation Of Cell Development Regulation Of Cell Growth Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development
Tagcloud ?		1n9 angus asb3 backfat corticotropin crossbreeding dermatan desaturase efemp1 epimerase fibulin gng3 hardy healthful heterosis linolenic marbling oleic overdominant palmitic parentage pltp sires slc27a1 slc27a2 solute wagyu wagyuxangus weinberg