HIP1R

Gene Name		huntingtin interacting protein 1 related
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Coated Pit Clathrin-coated Vesicle Clathrin-coated Vesicle Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Protein Binding, Bridging Phosphatidylinositol Binding
	Biological Process	Receptor-mediated Endocytosis Actin Cytoskeleton Organization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Parkinson's disease ( 21292315)
Protein-protein Interactions		8 interactors: ACTA1 CLTA CLTB CLTC CTTN DYNLL1 HIP1 HTT
Entrez ID		9026
HPRD ID		10412
Ensembl ID		ENSG00000130787
Uniprot IDs		B3KN98 B3KQW8 O75146 Q6NXG8
PDB IDs		1R0D
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Intracellular Protein Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cytoskeleton Organization Actin Cytoskeleton Organization Cellular Protein Localization Actin Filament-based Process Protein Transport Endocytosis Establishment Of Protein Localization Antigen Processing And Presentation Of Peptide Antigen Intracellular Transport Golgi Vesicle Transport Antigen Processing And Presentation Membrane Organization Transport Organelle Organization Protein Localization Establishment Of Localization In Cell Cell Differentiation Developmental Process Neural Plate Formation Post-Golgi Vesicle-mediated Transport Cellular Localization Anatomical Structure Morphogenesis Serotonin Uptake Skeletal Muscle Fiber Adaptation Lactate Biosynthetic Process From Pyruvate Regulation Of Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Protein Phosphatase Type 2A Activity Regulation Of Cell Death Mitotic Cell Cycle Process Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Transport Mitotic Cell Cycle Lactate Biosynthetic Process Cell Development Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Paraxial Mesoderm Formation Cellular Component Assembly Quinolinate Metabolic Process
Tagcloud ?		avoided balanced ccdc62 desipramine dextromethorphan escitalopram favorably fluoxetine gba gdnf haloperidol investigative lithium mapt neurogenesis neuroinflammation neuroprotective pathobiological pathobiology pramipexole priorities proteasomal psychotropics replicated rns safest salutary trophic valproate