CNTNAP1

Description		contactin associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Paranodal Junction Paranode Region Of Axon Anchoring Junction Glutamatergic Synapse
	Molecular Function	Protein Binding SH3 Domain Binding Signaling Receptor Activity
	Biological Process	Protein Localization To Paranode Region Of Axon Mitochondrion Organization Cytoskeleton Organization Cell Adhesion Signal Transduction Axonogenesis Central Nervous System Development Neuronal Action Potential Propagation Central Nervous System Myelination Myelination In Peripheral Nervous System Paranodal Junction Assembly Neuron Projection Development Myelination Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Neuromuscular Process Protein Localization To Juxtaparanode Region Of Axon Regulation Of Synapse Maturation Postsynaptic Density Organization Neuromuscular Junction Development, Skeletal Muscle Fiber Paranodal Junction Maintenance
Pathways		Neurofascin interactions
Drugs
Diseases
GWAS		Breast cancer ( 29059683) Major depressive disorder ( 27777418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: CCR4 FYN LCOR NFASC PTPRB RBM11 RHOA RTN4 SRC
Entrez ID		8506
HPRD ID		03825
Ensembl ID		ENSG00000108797
Uniprot IDs		P78357
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Migration Cell Motility Positive Regulation Of Podosome Assembly Phospholipase Activator Activity Regulation Of Podosome Assembly Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Neuron Migration Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Stimulatory C-type Lectin Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Phospholipase Binding Cellular Response To Lectin Ephrin Receptor Binding Glial Cell Migration Cerebral Cortex Cell Migration Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cell Junction Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Oxidative Stress Fc-gamma Receptor Signaling Pathway Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Telencephalon Cell Migration Regulation Of Cell Projection Organization Substrate Adhesion-dependent Cell Spreading Forebrain Cell Migration Regulation Of Reactive Oxygen Species Biosynthetic Process T Cell Costimulation Leukocyte Migration Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Cell Junction Assembly Positive Regulation Of T Cell Activation Ephrin Receptor Signaling Pathway Cellular Response To Chemical Stress Peptidyl-tyrosine Phosphorylation Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synapse Organization Negative Regulation Of Cell-substrate Adhesion Cell Differentiation Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Ficolin-1-rich Granule Membrane Actin Filament Bundle Organization Actin Filament Bundle Assembly See more
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