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PLEKHF1

Gene Name pleckstrin homology domain containing, family F (with FYVE domain) member 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Nucleus
  • Lysosome
  • Lysosomal Membrane
  • Endosome
  • Endosome Membrane
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Phosphatidylinositol-5-phosphate Binding
  • Phosphatidylinositol-3-phosphate Binding
  • Metal Ion Binding
  • Phosphatidylinositol-4-phosphate Binding
Biological Process
  • Apoptotic Process
  • Endosome Organization
  • Positive Regulation Of Autophagy
  • Vesicle Organization
  • Protein Localization To Plasma Membrane
  • Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions 3 interactors: KIAA1279 L3MBTL3 TNNT1
Entrez ID 79156
HPRD ID 15146
Ensembl ID ENSG00000166289
Uniprot IDs B4DWN9 Q96S99
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Slow-twitch Skeletal Muscle Fiber Contraction
  • Erythrocyte Maturation
  • Granulocyte Differentiation
  • Macrophage Differentiation
  • Negative Regulation Of Muscle Contraction
  • Skeletal Muscle Contraction
  • Muscle Filament Sliding
  • Actin-myosin Filament Sliding
  • Erythrocyte Development
  • Musculoskeletal Movement
  • Actin-mediated Cell Contraction
  • Actin Filament-based Movement
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